經濟部國家發明創作獎 | |
Phytochemistry, Pharmacology and Mode of Action of the Anti-Bacterial Artemisia Plants Bioengineering | |
Pharmacological and mechanistic study of PS1, a Pdia4 inhibitor, in β-cell pathogenesis and diabetes in db/db mice Cellular and Molecular Life Sciences | |
Early Life Exposure to C16-Ceramide Improves Learning and Short-Term Memory Behavior during Adulthood in Mice ACS Chemical Neuroscience | |
A Novel Phytogenic Formulation, EUBIO-BPSG, as a Promising One Health Approach to Replace Antibiotics and Promote Reproduction Performance in Laying Hens Bioengineering | |
Anti-coccidial properties and mechanisms of an edible herb, Bidens pilosa, and its active compounds for coccidiosis Scientific Reports | |
Glatiramer acetate enhances myeloid-derived suppressor cell function via recognition of paired Ig-like receptor B JOURNAL OF IMMUNOLOGY | |
Cytotoxic property of Streptocaulon baumii extracts and their isolated compounds against different human cancer cell lines Philippine Science Letters | |
Protein disulfide isomerase a4 acts as a novel regulator of cancer growth through the procaspase pathway Oncogene | |
Inhibiting MDSC differentiation from bone marrow with phytochemical polyacetylenes drastically impairs tumor metastasis Scientific Reports | |
Herbal remedies for coccidiosis control: A review of plants, compounds and anticoccidial actions Evidence-Based Complementary and Alternative Medicine | |
Field trial of medicinal plant, Bidens pilosa, against eimeriosis in broilers Scientific reports | |
Cytopiloyne, a polyacetylenic glucoside from Bidens pilosa, acts as a novel anticandidal agent via regulation of macrophages Journal of ethnopharmacology | |
Bidens pilosa and its active compound inhibit adipogenesis and lipid accumulation via down-modulation of the C/EBP and PPARgamma pathways Scientific reports | |
Beneficial effect of Bidens pilosa on body weight gain, food conversion ratio, gut bacteria and coccidiosis in chickens PLoS One | |
Data on the effect of Cytopiloyne against Listeria monocytogenes infection in mice Data in Brief | |
Naturally Occurring Anthraquinones: Chemistry and Therapeutic Potential in Autoimmune Diabetes Evidence-based Complementary and Alternative Medicine | |
Mechanistic Study of the Phytocompound, 2-β-D-Glucopyranosyloxy-1-hydroxytrideca-5,7,9,11-tetrayne in Human T-Cell Acute Lymphocytic Leukemia Cells by Using Combined Differential Proteomics and Bioinformatics Approaches Evidence-based Complementary and Alternative Medicine | |
Complementary and Alternative Medicine for Diabetes 2014 EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE | |
Effect of Bidens pilosa on infection and drug resistance of Eimeria in chickens Research in veterinary science | |
Mammalian target of rapamycin complex 2 (mTORC2) regulates LPS-induced expression of IL-12 and IL-23 in human dendritic cells JOURNAL OF LEUKOCYTE BIOLOGY | |
Ceramide inhibits insulin-stimulated Akt phosphorylation through activation of Rheb/mTORC1/S6K signaling in skeletal muscle Cellular Signalling | |
Botanical, Pharmacological, Phytochemical, and Toxicological Aspects of the Antidiabetic Plant L Evidence-Based Complementary and Alternative Medicine | |
Polarization and reprogramming of myeloid-derived suppressor cells Journal of molecular cell biology | |
Natural cures for type 1 diabetes: A review of phytochemicals, Biological actions, and clinical potential Current Medicinal Chemistry | |
Myeloid-Derived Suppressor Cells in Autoimmune Diabetes: Their Anti-diabetic Potential and Mechanism Journal of Diabetes & Metabolism | |
Morus alba and active compound oxyresveratrol exert anti-inflammatory activity via inhibition of leukocyte migration involving MEK/ERK signaling BMC complementary and alternative medicine | |
Herbal therapies for type 2 diabetes mellitus: chemistry, biology, and potential application of selected plants and compounds Evidence-Based Complementary and Alternative Medicine | |
Complementary and alternative medicine for diabetes Evidence-Based Complementary and Alternative Medicine | |
Botanical, Pharmacological, Phytochemical and Toxicological Aspects of the Anti-diabetic plant Bidens pilosa L Evidence-based Complementary and Alternative Medicine | |
Bidens pilosa L. (Asteraceae): Botanical Properties, Traditional Uses, Phytochemistry, and Pharmacology. Evidence-Based Complementary and Alternative Medicine | |
Anti-diabetic effect and mode of action of cytopiloyne Evidence-Based Complementary and Alternative Medicine | |
Shikonin induces immunogenic cell death in tumor cells and enhances dendritic cell-based cancer vaccine Cancer Immunology Immunotherapy | |
Shikonin enhances efficacy of a gene-based cancer vaccine via induction of RANTES Journal of Biomedical Science | |
Exendin-4 improves resistance to Listeria monocytogenes infection in diabetic db/db mice Journal of veterinary science | |
Curcumin induces the apoptosis of human monocytic leukemia THP-1 cells via the activation of JNK/ERK Pathways BMC complementary and alternative medicine | |
Catenarin Prevents Type 1 Diabetes in Nonobese Diabetic Mice via Inhibition of Leukocyte Migration Involving the MEK6/p38 and MEK7/JNK Pathways Evidence-Based Complementary and Alternative Medicine | |
Catenarin prevents type 1 diabetes in non-obese diabetic mice via inhibition of leukocyte migration involving the MEK6/p38 and MEK7/JNK pathways Evidence-Based Complementary and Alternative Medicine | |
Combined phytochemistry and chemotaxis assays for identification and mechanistic analysis of anti-inflammatory phytochemicals in Fallopia japonica PloS one | |
Anti-inflammatory properties of phenolic compounds and crude extract from Phorphyra dentata Journal of Ethnopharmacology | |
Anti-hyperglycemic properties of crude extract and triterpenes from Poria cocos Evidence-based Complementary and Alternative Medicine | |
Suppression of cell cycle progression by Jun dimerization protein 2 (JDP2) involves down-regulation of cyclin A2 ONCOGENE | |
Myeloid-derived suppressor cells prevent type 1 diabetes in murine models JOURNAL OF IMMUNOLOGY | |
Role of Cybr, a cytohesin binder and regulator, in CD4+ T-cell function and host immunity MOLECULAR IMMUNOLOGY | |
Anti-hyperglycemic effects and mechanism of Bidens pilosa water extract Journal of Ethnopharmacology | |
Anti-diabetic properties of three common Bidens pilosa variants in Taiwan PHYTOCHEMISTRY | |
咸豐草的功效 科學發展 | |
The effect of centaurein on interferon gamma expression and Listeria infection in mice TOXICOLOGY AND APPLIED PHARMACOLOGY | |
Flavonoids, centaurein and centaureidin, from Bidens pilosa, stimulate IFN-g expression Journal of Ethnopharmacology | |
Cytopiloyne, a Polyacetylenic Glucoside, Prevents Type 1 Diabetes in Non-obese Diabetic Mice JOURNAL OF IMMUNOLOGY | |
Cytopiloyne, a novel polyacetylenic glucoside from Bidens pilosa, functions as a T helper cell modulator Journal of Ethnopharmacology | |
Modulatory effects of Echinacea purpurea extracts on human dendritic cells: a cell- and gene-based study Genomics | |
The distinct effect of a butanol fraction of Bidens pilosa plant extract on the development of Th1-mediated diabetes and Th2-mediated airway inflammation in mice J Biomed Sci Journal of Biomedical Science | |
The SH3 domain of Tec kinase is essential for its targeting to activated CD28 costimulatory molecule EUROPEAN JOURNAL OF IMMUNOLOGY | |
Polyacetylenic compound and butanol fraction from Bidens pilosa Linn can modulate the differentiation of helper T cells and prevent autoimmune diabetes in nonobese diabetes mice Planta Medica | |
Tec kinase signaling in T cells is regulated by phosphatidylinositol 3-kinase and the Tec pleckstrin homology domain JOURNAL OF IMMUNOLOGY | |
Tec kinases: a family with multiple roles in immunity IMMUNITY | |
Role of Tec kinase in nuclear factor of activated T cells signaling INTERNATIONAL IMMUNOLOGY | |
The role of Tec protein-tyrosine kinase in T cell signaling Journal of Biological Chemistry | |
Tec kinase is involved in transcriptional regulation of IL-2 and IL-4 in the CD28 pathway EUROPEAN JOURNAL OF IMMUNOLOGY | |
國家農業科學獎 | |
Pdia4 regulates β-cell pathogenesis in diabetes: molecular mechanism and targeted therapy | |
On-Site Diagnosis of Poultry Coccidiosis by a Miniature Mass Spectrometer and Machine Learning ACS Agricultural Science & Technology | |
Agricultural Biotechnology Research Center Team Led by Wen-Chin Yang Received the National Agricultural Science Award from the Council of Agriculture, Executive Yuan. |  |
Functional and Mechanistic Studies of Two Anti-coccidial Herbs, Bidens pilosa and Artemisia indica Planta Medica | |
Protein disulfide isomerase a4 promotes lung cancer development via the Stat3 pathway in stromal cells Clinical and Translational Medicine Clinical and Translational Medicine | |
Glutamatergic Neurons Differentiated from Embryonic Stem Cells: An Investigation of Differentiation and Associated Diseases International Journal of Molecular Sciences | |
Identification of Novel Biomarkers for Pre-diabetic Diagnosis Using a Combinational Approach Frontiers in Endocrinology | |
Kansuinine A Ameliorates Atherosclerosis and Human Aortic Endothelial Cell Apoptosis by Inhibiting Reactive Oxygen Species Production and Suppressing IKKβ/IκBα/NF-κB Signaling International Journal of Molecular Sciences | |
Pdia4 regulates β‐cell pathogenesis in diabetes: molecular mechanism and targeted therapy EMBO Molecular Medicine | |
Sesamol Ameliorates Renal Injury-Mediated Atherosclerosis via Inhibition of Oxidative Stress/IKKα/p53 Antioxidants | |
Bidens pilosa: Nutritional Value and Benefits for Metabolic Syndrome eFood | |
Authentication, phytochemical characterization and anti-bacterial activity of twoArtemisiaspecies Food Chemistry | |
Toxicity study of Bidens pilosa in animals Journal of Traditional and Complementary Medicine | |
Phytochemicals as modulators of β-cells and immunity for the therapy of type 1 diabetes: Recent discoveries in pharmacological mechanisms and clinical potential Pharmacological Research | |
Ginkgolide A Prevents the Amyloid-β-Induced Depolarization of Cortical Neurons Journal of Agricultural and Food Chemistry | |
Development of the first-in-class diabetes drug, PS1 | |
R&D of a botanical drug for diabetes | |
Protein disulfide isomerase a4 acts as a novel regulator of cancer growth through the procaspase pathway | |
Research and development of Bidens pilosa for coccidiosis control | |
Terapeutic potential and mechanism of cytopiloyne | |
Myeloid-derived suppressor cells prevent type 1 diabetes in murine models | |
Cytopiloyne for preventing type 1 diabetes | |
2020未來科技獎 | |
2019台灣創新博覽會創新發明獎 | |
國家新創獎 | |
Lecture Award of Asia-Pacific Association of Agricultural Research Institutions (APAARI) | |
Outstanding Poster Award of APAARI | |
2018年台灣創新技術博覽會科技部展區重點技術 | |
中華天然藥物學會論文獎 | |
中華民國雜草學會 優良壁報論文獎 | |
2016年美洲華人生物學科學會(SCBA)最佳壁報論文獎 | |
2015年美洲華人生物學科學會(SCBA)最佳壁報論文獎 | |
台灣生醫暨新農業產業選秀大賽新農組潛力新秀獎 | |
第11屆國家新創獎 | |
經濟部智財局國家發明創作獎 | |
International Inventor prize
(國際發明家學術國光獎章) | |
科技部獎勵特殊優秀人才 | |
中研院前瞻計畫(2010 Career Development Award of Academia Sinica) | |
第六屆國家新創獎 | |
白蘭氏第四屆(2007)健康百萬論文獎優良論文指導教授 | |
用於腫瘤診斷及治療之多炔糖?衍生物的標靶PDIA4 Taiwan I570411 楊文欽 | |
Pdia4, target of cytopiloyne derivatives, for tumor diagnosis and treatment USA-regular US9382330B2 楊文欽 | |
治療糖尿病之組合物 Taiwan I522108 楊文欽 | |
Anti-coccidial prevention and treatment of Bidens pilosa and its phytochemicals PCT, USA-regular US 9072312B2 楊文欽,張力天 | |
咸豐草與其化合物預防與治療球蟲感染 Anti-coccidial prevention and treatment of Bidens pilosa and its phytochemicals Taiwan TW I 465242 楊文欽,張力天 | |
抑制白血球之CXC趨化素受器4型之虎丈萃取物及其製造方法 Taiwan TWI 422383 楊文欽,楊緒信,林雅俐,ClementMettling | |
Polyacetylenic compounds EP EP2384758 B1 楊文欽,張力天 | |
polyacetylenic compounds for protecting against pancreatic islet atrophy polyacetylenic compounds for protecting against pancreatic islet atrophy USA-regular US8575116 B1 楊文欽 | |
用於防止胰島萎縮症之聚炔類化合物 Taiwan TWI 412508 楊文欽 | |
POLYACETYLENIC COMPOUNDS FOR PROTECTING AGAINST PANCREATIC ISLET ATROPHY USA-regular US 8536141 楊文欽 | |
免疫調節之組合物 Taiwan TW I 377347 楊文欽,張書林,江一民,徐麗芬 | |
利用centaurein預防或治瘵胞內菌感染 Taiwan TW I 373341 楊文欽 | |
聚炔類化合物 Taiwan TWI 370738 楊文欽 | |
免疫調節之組合物 Taiwan TW I 369497 楊文欽,張書林,江一民,徐麗芬 | |
POLYACETYLENIC COMPOUNDS FOR STIMULATING INSULIN GENE EXRESSION, PRODUCTION AND SECRETION USA-regular US 8147880 B2 楊文欽 | |
BUTANOL EXTRACT OF BIDENS PILOSA USA-regular US 8048860 徐麗芬,江一民,張書林,張力天,楊文欽 | |
Polyacetylenic compounds EP EP1955701 楊文欽 | |
咸豐草之正丁醇萃取物 Taiwan TW I 347191 楊文欽,張書林,徐麗芬,江一民,張力天 | |
Polyacetylenic compounds USA-regular US7763285B2 楊文欽 | |
Immunomodulatory Compositions USA-regular 7691575 楊文欽,張書林,江一民,徐麗芬 | |
Antibacterial Treatment and Composition USA-regular 7341752 楊文欽 | |
Pdia4 regulates β-cell pathogenesis in diabetes: molecular mechanism and targeted therapy EMBO Molecular Medicine, e11668 |  |
Sitemap Wen-Chin Yang
| Wen-Chin Yang website |
| News (1) |
| Research (1) |
| Issued Patents (21) |
| Published Papers (72) |
| Research Findings (8) |
| Honors and Awards to ABRC Scientists (20) |
Faculty
