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論文著作

論文著作 (2016)
Molecular basis of shikonin-induced immunogenic cell death: insights for developing cancer therapeutics
Receptors & Clinical Investigation
論文著作 (2016)
Induction of IL-25 secretion from tumour-associated fibroblasts suppresses mammary tumour metastasis
Nature Communications
論文著作 (2016)
Immunogenicity of mammary tumor cells can be induced by shikonin via direct binding-interference with hnRNPA1
Oncotarget
論文著作 (2016)
Inhibiting MDSC differentiation from bone marrow with phytochemical polyacetylenes drastically impairs tumor metastasis
Scientific Reports
論文著作 (2015)
Specific Medicinal Plant Polysaccharides Effectively Enhance the Potency of a DC-Based Vaccine against Mouse Mammary Tumor Metastasi
PLoS One
論文著作 (2015)
Mammalian target of rapamycin complex 2 (mTORC2) regulates LPS-induced expression of IL-12 and IL-23 in human dendritic cells
Journal of Leukocyte Biology
論文著作 (2015)
Shikonin-enhanced cell immunogenicity of tumor vaccine is mediated by the differential effects of DAMP components
Molecular Cancer
論文著作 (2015)
Rapamycin Promotes Mouse 4T1 Tumor Metastasis that Can Be Reversed by a Dendritic Cell-Based Vaccine
PLoS One
論文著作 (2014)
Tumor-associated antigen/IL-21-transduced dendritic cell vaccines enhance immunity and inhibit immunosuppressive cells in metastatic melanoma
Gene Therapy
論文著作 (2013)
The Phytochemical Shikonin Stimulates Epithelial-Mesenchymal Transition (EMT) in Skin Wound Healing
Evidence-based Complementary and Alternative Medicine
論文著作 (2013)
Integration of different “-omics” technologies identifies inhibition of the IGF1R-Akt-mTOR signaling cascade involved in the cytotoxic effect of shikonin against leukemia cells
Evidence-based Complementary and Alternative Medicine
論文著作 (2013)
Dietary Uptake of Wedelia chinensis Extract Attenuates Dextran Sulfate Sodium-induced Colitis in Mice
PLoS One
論文著作 (2013)
Therapeutic Applications of Herbal Medicines for Cancer Patients
Evidence-based Complementary and Alternative Medicine
論文著作 (2013)
Specific Dioscorea phytoextracts enhance potency of TCL-loaded DC-based cancer vaccine
Evidence-based Complementary and Alternative Medicine
論文著作 (2013)
Anti-inflammatory activities of natural products isolated from soft corals of Taiwan between 2008–2012
Marine Drugs
論文著作 (2012)
Shikonin enhances efficacy of a gene-based cancer vaccine via induction of RANTES
J. Biomed. Sci.
論文著作 (2012)
Ferulic acid, a phenolic phytochemical, inhibits UVB-induced matrix metalloproteinases in mouse skin vai post-translational mechanisms
Journal of Nutritional Biochemistry
論文著作 (2012)
Dietary administration of scallion extract effectively inhibits colorectal tumor growth: Cellular and molecular mechanisms
PLoS One
論文著作 (2012)
Shikonin induces immunogenic cell death in tumor cells and enhances dendritic cell-based cancer vaccine
Cancer Immunology Immunotherapy
論文著作 (2011)
Topical application of marine briarane-type diterpenes effectively inhibits 12-O-tetradecanoylphorbol-13-acetate-induced inflammation and dermatitis in murine skin
Journal of Biomedical Science
論文著作 (2011)
Dioscorea phytocompounds synergistically enhance interleukin-2-mediated murine splenocyte proliferation ex vivo and improve regeneration of bone marrow cells in vivo
Evidence-based Complementary and Alternative Medicine
論文著作 (2011)
Specific microtubule-depolymerizing agents augment effcacy of dendritic cell-based cancer vaccine
Journal of Biomedical Science
論文著作 (2011)
Interleukin-4 enhances trafficking and functional activities of GM-CSF-stimulated mouse myeloid-derived dendritic cells at late differentiation stage
Experimental Cell Research
論文著作 (2010)
Cytotoxic C-35 Terpenoid Cryptotrione from the Bark of Cryptomeria japonica
Organic Letters
論文著作 (2010)
Anti-Inflammatory Plant Natural Products for Cancer Therapy
Planta Medica
論文著作 (2010)
Differential functional genomic effects of anti-inflammatory phytocompounds on immune signaling
BMC Genomics
論文著作 (2010)
Stimulatory effect of Echinacea purpurea extract on the trafficking activity of mouse dendritic cells: revealed by genomic and proteomic analyses
BMC Genomics
論文著作 (2010)
Comparative metabolomics approach coupled with cell- and gene-based assays for species classification and anti-inflammatory bioactivity validation of Echinacea plants
Journal of Nutritional Biochemistry
論文著作 (2009)
Protective immunity against porcine circovirus 2 in mice induced by a gene-based combination vaccination
The Journal of Gene Medicine
論文著作 (2009)
Functional genomics of immuno-modulatory activities of medicinal plant extracts/phytocompounds in human dendritic cells/monocytes
Planta Medica
論文著作 (2009)
Transgenic expression of human gp100 and RANTES at specific time points for suppression of melanoma
Gene Therapy
論文著作 (2008)
Metabolomics for phytomedicine research and drug development
Current Opinion in Chemical Biology
論文著作 (2008)
Genomics and proteomics of immune modulatory effects of a butanol fraction of echinacea purpurea in human dendritic cells
BMC Genomics
論文著作 (2008)
Immunomodulatory effects of phytocompounds characterized by in vivo transgenic human GM-CSF promoter activity in skin tissues
Journal of Biomedical Science
論文著作 (2007)
Cytotoxic and novel skeleton compounds from the heartwood of Chamaecyparis obtusa var formosana
Tetrahedron Letters
論文著作 (2007)
Inhibition of tumor necrosis factor-alpha through selective blockade of pre-mRNA splicing by shikonin
Molecular Pharmacology
論文著作 (2007)
A galactolipid possesses novel cancer chemopreventive effects by suppressing inflammatory mediators and mouse B16 melanoma
Cancer Research
論文著作 (2007)
Specific plant terpenoids and lignoids possess potent antiviral activities against severe acute respiratory syndrome coronavirus
Journal of Medicinal Chemistry
論文著作 (2006)
DNA vaccination against foot-and-mouth disease via electroporation: Study of molecular approaches for enhancing VP1 antigenicity.
The Journal of Gene Medicine
論文著作 (2006)
Caffeic acid suppresses UVB radiation-induced expression of interleukin-10 and activation of mitogen-activated protein kinases in mouse
Carcinogenesis
論文著作 (2006)
Modulatory effects of Echinacea purpurea extracts on human dendritic cells: A cell- and gene-based study
Genomics
論文著作 (2005)
A glycine-rich protein gene family predominantly expressed in tomato roots, but not in leaves and ripe fruit
Plant Science
論文著作 (2005)
Comparative studies of the capsid precursor polypeptide P1 and the capsid protein VP1 cDNA vectors for DNA vaccination against foot-and-mouth diseases virus
The Journal of Gene Medicine
論文著作 (2005)
A truncated Fibrobacter succinogenes 1,3-1,4-beta-d-glucanase with improved enzymatic activity and thermotolerance
Biochemistry
論文著作 (2005)
Ethyl caffeate suppresses NF-kappaB activation and its downstream inflammatory mediators, iNOS, COX-2, and PGE2 in vitro or in mouse skin
British Journal of Pharmacology
論文著作 (2004)
Molecular strategies for improving cytokine transgene expression in normal and malignant tissues
Gene Therapy
論文著作 (2004)
Shikonins, phytocompounds from Lithospermum erythrorhizon, inhibit the transcriptional activation of human tumor necrosis factor alpha promoter in vivo
Journal of Biological Chemistry
論文著作 (2004)
Medicinal herb extract and a single-compound drug confer similar complex pharmacogenomic activities in MCF-7 cells
Journal of Biomedical Science
論文著作 (2004)
Expression of bioactive human interferon-gamma protein in transgenic rice suspension cells
Transgenic Research
論文著作 (2004)
Induction of apoptosis in MCF-7 human breast cancer cells by phytochemicals from Anoectochilus formosanus
Journal of Biomedical Science
論文著作 (2004)
Transgenic tomato plants expressing the Arabidopsis NPR1 gene display enhanced resistance to a spectrum of fungal and bacterial diseases
Transgenic Research
論文著作 (2003)
Tissue Array Transgene Expression System for the Evaluation of Effect of Medicinal Herbs on Wound-healing
Journal of Genetics and Molecular Biology
論文著作 (2003)
In silico identification and phylogenetic analysis of putative plant arylalkylamine N-acetyl-transferase
J Genet Mol Biol
論文著作 (2003)
Antioxidant properties and phytochemical characteristics of extracts from Lactuca indica
Journal of Agricultural and Food Chemistry
論文著作 (2003)
The sweet pepper ferredoxin-like protein (pflp) conferred resistance against soft rot disease in Oncidium orchid
Transgenic Research
論文著作 (2003)
Agrobacterium tumefaciens-mediated transformation of an Oncidium orchid
Plant Cell Reports
論文著作 (2003)
Tissue array transgene expression system for the evolution of effect of medicinal herbs on wound-healing
Journal of Genetics and Molecular Biology
論文著作 (2003)
In Silico identification and phylogenetic analysis of an unique GNAT-type of acetyltransferases in plants
Journal of Genetics and Molecular Biology
論文著作 (2002)
Profiling and characterization of antioxidant activities in Anoectochilus formosanus Hayata
Journal of Agricultural and Food Chemistry
論文著作 (2002)
Direct gene transfer and vaccination via skin transfection using a gene gun
Methods in Molecular Medicine
論文著作 (2002)
Profiling and characterization antioxidant activities in Anoectochilus formosanus hayata
Journal of Agricultural and Food Chemistry
論文著作 (2002)
Relative promoter strengths in four human prostate cancer cell lines evaluated by particle bombardment-mediated gene transfer
The Prostate
論文著作 (2002)
Mutagenesis of Trp(54) and Trp(203) residues on Fibrobacter succinogenes 1,3-1,4-beta-D-glucanase significantly affects catalytic activities of the enzyme
Biochemistry
論文著作 (2002)
Intratumoral injection of interleukin-12 plasmid DNA, either naked or in complex with cationic lipid, results in similar tumor regression in a murine model
Molecular Cancer Therapeutics
論文著作 (2002)
Immunization by particle-mediated transfer of the granulocyte-macrophage colony-stimulating factor gene into autologous tumor cells in melanoma or sarcoma patients: report of a phase I/IB study
Human Gene Therapy
論文著作 (2002)
Fas-Fas ligand signaling pathway mediates an interleukin-12-induced rejection of a murine prostate tumor system
The Prostate
論文著作 (2001)
Truncated glucanase with enhanced activity and method for making the same
US and ROC patent
論文著作 (2001)
Interleukin-12 gene transfer into skin distant from the tumor site elicits antimetastatic effects equivalent to local gene transfer
Human Gene Therapy
論文著作 (2001)
Effective particle-mediated vaccination against mouse melanoma by coadministration of plasmid DNA encoding Gp100 and granulocyte-macrophage colony-stimulating factor
Clinical Cancer Research
論文著作 (2001)
Antioxidant activity of extracts from Acacia confusa bark and heartwood
Journal of Agricultural and Food Chemistry
論文著作 (2000)
The use of particle-mediated gene transfer for the study of promoter activity in somatic tissues
Methods in Molecular Biology
論文著作 (2000)
Regulation of cell proliferation, gene expression, production ofcytokines, and cell cycle progression in primary human T lymphocytes b
Mol Pharmacol
論文著作 (2000)
Interleukin-12 gene therapy of a weakly immunogenic mouse mammary carcinoma results in reduction of spontaneous lung metastases via a T-cell-independent mechanism
Cancer Gene Therapy
論文著作 (2000)
Regulation of cell proliferation, gene expression, production of cytokines, and cell cycle progression in primary human T lymphocytes by piperlactam S isolated from Piper kadsura
Molecular Pharmacology
論文著作 (1999)
Preclinical development of human granulocyte-macrophage colony-stimulatingfactor-transfected melanoma cell vaccine using established canine cel
Cancer Gene Therapy
論文著作 (1999)
Inhibition of tumor growth in Lewis lung carcinoma in mice by combination of mIL-12 and IL-18 cDNA
Am J Respir Crit Care Med
論文著作 (1999)
Gene gun-mediated IL-12 gene therapy induces antitumor effects in theabsence of toxicity: a direct comparison with systemic IL-12 protei
J Immunother
論文著作 (1999)
Preclinical development of human granulocyte-macrophage colony-stimulating factor-transfected melanoma cell vaccine using established canine cell lines and normal dogs
Cancer Gene Therapy
論文著作 (1999)
Gene gun-mediated IL-12 gene therapy induces antitumor effects in the absence of toxicity: a direct comparison with systemic IL-12 protein therapy
Journal of Immunotherapy
論文著作 (1999)
Interleukin-12 cDNA skin transfection potentiates human papillomavirus E6 DNA vaccine-induced antitumor immune response
Cancer Gene Therapy
論文著作 (1999)
Synergistic inhibition of tumor growth in a murine mammary adenocarcinoma model by combinational gene therapy using IL-12, pro-IL-18, and IL-1beta converting enzyme cDNA
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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論文著作 (81)
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