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論文著作 (2019)
Blockage of glutamine-dependent anaplerosis affects mTORC1/2 activity and ultimately leads to cellular senescence-like response
BIOLOGY OPEN
論文著作 (2018)
Necroptosis promotes autophagy-dependent upregulation of DAMP and results in immunosurveillance
Autophagy
論文著作 (2018)
Transcriptomic analysis reveals a controlling mechanism for NLRP3 and IL-17A in dextran sulfate sodium (DSS)-induced colitis
Scientific Reports
論文著作 (2018)
O-Glycosylation–mediated signaling circuit drives metastatic castration-resistant prostate cancer
FASEB JOURNAL
論文著作 (2018)
The extracellular SEMA domain attenuates intracellular apoptotic signaling of semaphorin 6A in lung cancer cells
Oncogenesis
論文著作 (2017)
A virus-like particle vaccination strategy expands its tolerance to H3N2 antigenic drift by enhancing neutralizing antibodies against hemagglutinin stalk
Antiviral Research
論文著作 (2017)
A Standardized Wedelia chinensis extract overcomes the Feedback activation of HER2/3 signaling upon androgen-ablation in prostate cancer
Frontiers in Pharmacology
論文著作 (2017)
A Standardized Wedelia chinensis extract mitigates tumor inflammation and augments chemotherapy effect of docetaxel in prostate cancer
SCIENTIFIC REPORTS
論文著作 (2016)
Development of single-chain variable fragments (scFv) against influenza virus targeting hemagglutinin subunit 2 (HA2)
Archives of Virology
論文著作 (2016)
A novel H6N1 virus-like particle vaccine induces long-lasting cross-clade antibody immunity against human and avian H6N1 viruses
Antiviral Research
論文著作 (2016)
Induction of IL-25 secretion from tumour-associated fibroblasts suppresses mammary tumour metastasis
Nature Communications
論文著作 (2016)
Immunogenicity of mammary tumor cells can be induced by shikonin via direct binding-interference with hnRNPA1
Oncotarget
論文著作 (2016)
Metastatic progression of prostate cancer is mediated by autonomous binding of galectin-4-O-glycan to cancer cells
Cancer Research
論文著作 (2015)
Development of a standardized and effect-optimized herbal extract of Wedelia chinensis for prostate cancer
Phytomedicine
論文著作 (2015)
Androgen-Induced TMPRSS2 Activates Matriptase and Promotes Extracellular Matrix Degradation, Prostate Cancer Cell Invasion, Tumor Growth, and Metastasis
Cancer Research
論文著作 (2015)
Inactivated enterovirus 71 vaccine produced by 200-l scale serum-free microcarrier bioreactor system provides cross-protective efficacy in human SCARB2 transgenic mouse
PLoS One
論文著作 (2015)
Shikonin-enhanced cell immunogenicity of tumor vaccine is mediated by the differential effects of DAMP components
Molecular Cancer
論文著作 (2015)
Novel Cancer Therapeutics with Allosteric modulation of the mitochondrial c-Raf-DAPK complex by Raf inhibitor combination therapy
Cancer Research
論文著作 (2015)
Rapamycin Promotes Mouse 4T1 Tumor Metastasis that Can Be Reversed by a Dendritic Cell-Based Vaccine
PLoS One
論文著作 (2015)
Anticancer efficacy of unique pyridine-based tetraindoles
European journal of medicinal chemistry
論文著作 (2014)
Rapid and sensitive early diagnosis of influenza virus subtype via surface enhanced Raman scattering
J Biosens Bioelectron
論文著作 (2014)
The tetraindole SK228 reverses the epithelial-to-mesenchymal transition of breast cancer cells by up-regulating members of the miR-200 family
PLoS ONE
論文著作 (2014)
Squalene-adjuvanted H7N9 virus vaccine induces robust humoral immune response against H7N9 and H7N7 viruses
Vaccine
論文著作 (2014)
HAI-2 suppresses the invasive growth and metastasis of prostate cancer through regulation of matriptase
ONCOGENE
論文著作 (2014)
Pharmacologic Down-regulation of EZH2 Suppresses Bladder Cancer in vitro and in vivo
Oncotarget
論文著作 (2013)
Dietary uptake of Wedelia chinensis extract attenuates dextran sulfate sodium-induced colitis in mice
PLoS One
論文著作 (2013)
Curcumin-targeting pericellular serine protease matriptase role in suppression of prostate cancer cell invasion, tumor growth and metastasis
Cancer Prevention Research
論文著作 (2013)
Histone demethylase retinoblastoma binding protein-2 promotes lung tumorigenesis and cancer metastasis
Cancer Research
論文著作 (2012)
A VLP Vaccine Induces broad-spectrum cross-protective antibody immunity against H5N1 and H1N1 subtypes of influenza a virus
PLoS One
論文著作 (2012)
TET1 suppresses cancer invasion by activating the tissue inhibitors of metalloproteinases
Cell Reports
論文著作 (2011)
A Cullin3-KLHL20 ubiqutin ligase-dependent pathway targets PML to amplify HIF-1 signaling and tumor hypoxia responses
CANCER CELL
論文著作 (2010)
Mammalian expression of virus-like particles for advanced mimicry of authentic influenza virus
PLoS One
論文著作 (2009)
Dual Degradation of Aurora A and B Kinases by the Histone Deacetylase Inhibitor LBH589 Induces G2-M Arrest and Apoptosis of Renal Cancer Cells
CLINICAL CANCER RESEARCH
論文著作 (2009)
Herbal Extract of Wedelia chinensis Attenuates Androgen Receptor Activity and Orthotopic Growth of Prostate Cancer in Nude Mice
CLINICAL CANCER RESEARCH
論文著作 (2008)
A novel diterpene suppresses CWR22Rv1 tumor growth in vivo through anti-proliferation and pro-apoptosis
Cancer Research
論文著作 (2008)
Crucial Role of Estrogen Receptor-α Interaction with Transcription Coregulators in Follicle-StimulatingHormone and Transforming Growth Factor β1 Up-Regulation of Steroidogenesis in Rat Ovarian Granulosa Cells
ENDOCRINOLOGY
論文著作 (2007)
Interplay of PI3K and cAMP/PKA signaling, and rapamycin-hypersensitivity in TGFß1 enhancement of FSH-stimulated steroidogenesis in rat ovarian granulosa cells
JOURNAL OF ENDOCRINOLOGY
論文著作 (2007)
Critical involvement of ILK in TGFβ1-stimulated invasion/migration of human ovarian cancer cells is associated with urokinase plasminogen activator system
Experimental Cell Research
論文著作 (2007)
Specific plant terpenoids and Ligands Possess potent antiviral activities against severe acute respiratory syndrome coronavirus
Journal of Medicinal Chemistry
論文著作 (2007)
Diterpenes from Cryptomeria japonica Inhibit Androgen Receptor Transcriptional Activity in Prostate Cancer Cells
Planta Medica
論文著作 (2007)
Compounds from Wedelia chinensis synergistically suppress androgen activity and growth in prostate cancer cells
CARCINOGENESIS
論文著作 (2004)
Early detection of antibodies against various structural proteins of the SARS-associated coronavirus in SARS patients
Journal of Biomedical Science
論文著作 (2004)
Characterization of two mosquito STATs, AaSTAT and CtSTAT: Differential regulation of tyrosine hosphorylation and DNA binding activity by LPS treatment and by Japanese encephalitis virus infection
Journal of Biological Chemistry
論文著作 (2003)
BAF60a mediates critical interactions between nuclear receptors and the BRG1 chromatin-remodeling complex for transactivation
MOLECULAR AND CELLULAR BIOLOGY
論文著作 (2002)
Chromatin remodeling and tissue-selective responses of nuclear hormone receptors
BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE
論文著作 (2000)
Differential regulation of testosterone vs. 5 α-dihydrotestosterone by selective androgen response elements
MOLECULAR AND CELLULAR BIOCHEMISTRY
論文著作 (1999)
The linkage of Kennedy's disease to Ran/ARA24, identified as the first androgen receptor poly-glutamine region associated coactivator
Journal of Biological Chemistry
論文著作 (1999)
Isolation and characterization of ARA160 as the first androgen receptor N-terminal associated coactivator in human prostate cells
Journal of Biological Chemistry
徵才 2022-02-10
【蕭培文實驗室】誠徵學士/碩士級助理
論文著作 (2021)
Increase in Akkermansiaceae in Gut Microbiota of Prostate Cancer-Bearing Mice
International Journal of Molecular Sciences
論文著作 (2021)
CD28 engagement inhibits CD73-mediated regulatory activity of CD8+T cells
Communications Biology
論文著作 (2021)
Comparison of Chicken Immune Responses after Inoculation with H5 Avian Influenza Virus-like Particles Produced by Insect Cells or Pupae
JOURNAL OF VETERINARY RESEARCH
論文著作 (2021)
Arginine is an epigenetic regulator targeting TEAD4 to modulate OXPHOS in prostate cancer cells
NATURE COMMUNICATIONS
論文著作 (2021)
Sesquiterpene Lactone Deoxyelephantopin Isolated from Elephantopus scaber and Its Derivative DETD-35 Suppress BRAF V600E Mutant Melanoma Lung Metastasis in Mice
International Journal of Molecular Sciences
論文著作 (2021)
Sialyltransferase Inhibitors Suppress Breast Cancer Metastasis
Journal of Medicinal Chemistry
論文著作 (2020)
Inhibition of TMPRSS2 by HAI-2 reduces prostate cancer cell invasion and metastasis
ONCOGENE
論文著作 (2020)
Deregulating the CYP2C19/Epoxy-Eicosatrienoic Acid-Associated FABP4/FABP5 Signaling Network as a Therapeutic Approach for Metastatic Triple-Negative Breast Cancer
Cancers
論文著作 (2019)
The mature EV71 virion induced a broadly cross-neutralizing VP1 antibody against subtypes of the EV71 virus
PLOS ONE
重要發現與突破 (2018)
O-鏈型醣化調節癌化信息驅動攝護腺癌產生轉移與荷爾蒙抗性
重要發現與突破 (2017)
黃花蜜菜標準化草藥調整攝護腺腫瘤發炎反應及改善克癌易化療的結果
重要發現與突破 (2017)
黃花蜜菜標準化草藥有效抑制攝護腺癌對荷爾療法產生抗性
重要發現與突破 (2016)
自主性galectin-4結合癌細胞表面的O型醣鏈造成攝護腺癌惡化轉移
重要發現與突破 (2010)
研發流感疫苗的尖端科技:利用哺乳動物細胞表現之類病毒顆粒模擬流感病毒
重要發現與突破 (2009)
黃花蜜菜天然抽出物抑制雄性素受體活性與前列腺腫瘤之原位生長
重要發現與突破 (2008)
新的二萜類化合物能藉由抑制雄性素受體、細胞增生與促細胞凋零達而致抗前列腺癌功效
重要特殊獎項 (2011-10)
8th, National Innovation Award (Academic Research Group, Food Category) by Institute for Biotechnology and Medicine Industry on “Wedelia chinensis extract modulates prostate cancer, benign prostatic hyperplasia (BPH) and androgen-regulated disease”.
重要特殊獎項 (2011-10)
8th National Innovation Award (Academic Research Group, Pharmacy Category) by Institute for Biotechnology and Medicine Industry on "Applications of Mammalian-expressed Influenza Virus-like Particles (VLPs) for Vaccine/ Antibody Manufacture and Virus Diagn
重要特殊獎項 (2010-12)
The 2011 Academia Sinica Career Development Award
專利
TRANSCRIPTION MODULATOR COMPOSITIONS
USA-regular US 9144591
蕭培文
專利
產生類病毒微粒之高產率轉殖基因哺乳動物表現系統
Taiwan TWI 494430
蕭培文,吳佳穎,葉怡均
專利
High yield transgenic mammalian expression system for generating virus-like particles
USA-regular US 8980281
蕭培文,吳佳穎,葉怡均
專利
二帖類化合物於治療攝護腺癌之用途
Taiwan TWI 434680
蕭培文,林楓閔,王升陽
專利
Transcription Modulator Compositions
USA-regular US8,597,701 B2
蕭培文
專利
Use of diterpene,6-hydroxy-5,6-dehydrosugiol,and its derives in treatment of prostate cancer
USA-regular US8519007
蕭培文,林楓閔,王升陽
專利
轉錄調控組合物
Taiwan TW I 405966
蕭培文
專利
Transcription Modulator Compositions
China CN 101313926B
蕭培文
專利
產生類病毒微粒之高產率轉殖基因哺乳動物表現系統
Taiwan TW I 340166
蕭培文,楊寧蓀,黃銓珍,林恩豪
專利
轉錄調控物組合物
Taiwan TW I324521
蕭培文
最新研究 (2021)
地膽草倍半萜內酯deoxyelephantopin及其衍生物 DETD-35 抑制BRAFV600E突變種黑色素瘤在小鼠體內之肺轉移
International Journal of Molecular Sciences, 2021, 22(6), 3226

演講訊息 (2021)
Exploring the Tumor Immune Microenvironment (TIME) by Tissue-Based Biomarker Measurements
游舒涵博士 (國立臺灣大學生物科技研究所助理教授)
2021/08/09 11:00 AM Webex 線上演講
網站導覽 蕭培文
最新研究 (1)
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徵才 (1)
專利 (10)
論文著作 (57)
重要發現與突破 (7)
重要特殊獎項 (3)
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