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徵才 2022-09-8
【徐麗芬研究室】誠徵研究助理/博士後研究員-植物天然藥物之研究
最新研究 (2022)
植物倍半萜內酯deoxyelephantopin (DET)和其新穎衍生物藉抑制GPX4酵素、重整代謝以及引起ferroptosis達到抑制藥性敏感或抗藥性BRAFV600E黑色素瘤生長
Pharmacological Research, 178, 106148. (doi.org/10.1016/j.phrs.2022.106148)

論文著作 (2019)
Cumingianoside A, a Phyto-Triterpenoid Saponin Inhibits Acquired BRAF Inhibitor Resistant Melanoma Growth via Programmed Cell Death
Frontiers in Pharmacology
論文著作 (2019)
Phyto-sesquiterpene lactone deoxyelephantopin and cisplatin synergistically suppress lung metastasis of B16 melanoma in mice with reduced nephrotoxicity
Phytomedicine
論文著作 (2019)
Essential oil of Mentha aquatica var. Kenting Water Mint suppresses two-stage skin carcinogenesis accelerated by BRAF inhibitor vemurafenib.
Molecules
論文著作 (2018)
Plant galactolipid dLGG suppresses lung metastasis of melanoma through deregulating TNF-alpha-mediated pulmonary vascular permeability and circulating oxylipin dynamics in mice
International Journal of Cancer
論文著作 (2018)
Dual specificity phosphatase DUSP6 promotes endothelial inflammation through inducible expression of ICAM-1
The FEBS Journal
論文著作 (2017)
Metabolomic compounds identified in Piriformospora indica-colonized Chinese cabbage roots delineate symbiotic functions of the interaction
Scientific Reports
論文著作 (2017)
Novel effect and the mechanistic insights of fruiting body extract of medicinal fungus Antrodia cinnamomea against T47D breast cancer
Phytomedicine
論文著作 (2017)
Phytoagent deoxyelephantopin derivative inhibits triple negative breast cancer cell activity by inducing oxidative stress-mediated paraptosis-like cell death
Oncotarget
論文著作 (2017)
Phytoagent deoxyelephantopin and its derivative inhibit triple negative breast cancer cell activity through ROS-mediated exosomal activity and protein functions
Frontiers in Pharmacology
論文著作 (2016)
Phytomedicine polypharmacology: Cancer therapy through modulating the tumor microenvironment and oxylipin dynamics
Pharmacology and Therapeutics
論文著作 (2016)
Novel sesquiterpene lactone analogues as potent anti-breast cancer agents
Molecular Oncology
論文著作 (2016)
A novel plant sesquiterpene lactone derivative DETD-35 suppresses BRAFV600E mutant melanoma growth and overcomes acquired vemurafenib resistance in mice
MOLECULAR CANCER THERAPEUTICS
論文著作 (2016)
Phytomedicine-Modulating oxidative stress and the tumor microenvironment for cancer therapy
Pharmacological Research
論文著作 (2016)
Copper supplementation amplifies the anti-tumor effect of curcumin in oral cancer cells
Phytomedicine
論文著作 (2015)
Structural and functional roles of glycosylation in fungal laccase from Lentinus sp
PLoS ONE
論文著作 (2015)
Simvastatin and a plant galactolipid protect animals from septic shock by regulating oxylipin mediator dynamics through the MAPK-cPLA2 signaling pathway
Molecular Medicine
論文著作 (2015)
Pu-erh tea polysaccharides decrease blood sugar by inhibition alpha-glucosidase activities in vitro and in mice
Food & Function
論文著作 (2015)
New alkaloids from Formosan zoanthid Zoanthus kuroshio
Tetrahedron
論文著作 (2015)
Mechanistic study of the phytocompound, 2-beta-D-glucopyranosyloxy-1-hydroxytrideca-5,7,9,11-tetrayne in human T-Cell acute lymphocytic leukemia cells by using combined differential proteomics and bioinformatics approaches
Evidence-based Complementary and Alternative Medicine
論文著作 (2015)
Mammalian target of rapamycin complex 2 (mTORC2) regulates LPS-induced expression of IL-12 and IL-23 in human dendritic cells
Journal of Leukocyte Biology
論文著作 (2013)
Phytoagents for cancer management: regulation of nucleic acid oxidation, ROS, and related mechanisms
Oxidative Medicine and Cellular Longevity
論文著作 (2013)
Herbal medicine and acupuncture for breast cancer palliative care and adjuvant therapy
Evidence-based Complementary and Alternative Medicine
論文著作 (2013)
Hepatoprotective effect and mechanistic insights of deoxyelephantopin, a phyto-sesquiterpene lactone, against fulminant hepatitis
Journal of Nutritional Biochemistry
論文著作 (2013)
A plant kavalactone desmethoxyyangonin prevents inflammation and fulminant hepatitis in mice
PLoS ONE
論文著作 (2012)
Taxol, camptothecin and beyond for cancer therapy
Advances in Botanical Research
論文著作 (2012)
Silibinin and Paclitaxel Cotreatment Significantly Suppress the Activity and Lung Metastasis of Triple Negative 4T1 Mammary Tumor Cell in Mice
Journal of Traditional and Complementary Medicine
論文著作 (2012)
Recombinant viral protein VP1 suppresses HER-2 expression and migration/metastasis of breast cancer
Breast Cancer Research and Treatment
論文著作 (2012)
Engineering of dual functional hybrid glucanases
Protein Engineering Design & Selection
論文著作 (2012)
Deoxyelephantopin impedes mammary adenocarcinoma cell motility through inhibiting calpain-mediated adhesion dynamics and inducing ROS and aggresome formation
Free Radical Biology & Medicine
論文著作 (2012)
Biochemical characterization of a novel laccase from the basidiomycete fungus Cerrena sp. WR1
Protein Engineering Design & Selection
論文著作 (2012)
Biological degradation of anthroquinone and azo dyes by a novel laccase from Lentinus sp
Environmental Science and Technology
論文著作 (2011)
Traditional Chinese medicine herbal extracts of Cibotium barometz, Gentiana scabra, Dioscorea batatas, Cassia tora, and Taxillus chinensis inhibit SARS-CoV replication
Journal of Traditional and Complementary Medicine
論文著作 (2011)
Structural basis for the inhibition of 1,3-1,4-β-D-glucanase by noncompetitive calcium ion and competitive Tris inhibitors
Biochemical and Biophysical Research Communication
論文著作 (2011)
Dioscorea phytocompounds enhance murine splenocyte proliferation ex vivo and improve regeneration of bone marrow cells in vivo
Evidence-based Complementary and Alternative Medicine
論文著作 (2011)
Crystal structures of the laminarinase catalytic domain from Thermotoga maritima MSB8 in complex with inhibitors: essential residues for β-1,3 and β-1,4 glucan selection
Journal of Biological Chemistry
論文著作 (2011)
A sesquiterpenol extract potently suppresses inflammation in macrophages and mice skin and prevents chronic liver damage in mice through JNK-dependent HO-1 expression
Phytochemistry
論文著作 (2011)
Echinacea alkamides prevent lipopolysaccharide/D-galactosamineinduced acute hepatic injury through JNK pathway-mediated HO-1 expression
Journal of Agricultural and Food Chemistry
論文著作 (2010)
Use of Anoectochilus formosanus plant extracts and their derived fractions as herbal medicines or nutraceutical supplements for tumor prevention/treatment
Malaysia patent
論文著作 (2010)
Taiwanin A inhibits MCF-7 cancer cell activity through induction of oxidative stress, upregulation of DNA damage checkpoint kinases, and activation of p53 and FasL/Fas signaling pathways
Phytomedicine
論文著作 (2010)
Structural and catalytic roles of amino acid residues located at substrate binding pocket in Fibrobacter succinogenes 1,3-1,4-beta-D-glucanase
PROTEINS: Structure, Function, and Bioinformatics
論文著作 (2010)
Deoxyelephantopin, a novel multifunctional agent suppresses mammary tumor growth and lung metastasis and doubles survival time in mice
British Journal of Pharmacology
論文著作 (2010)
Current research and development of chemotherapeutic agents for melanoma
Cancers
論文著作 (2010)
Differential proteomic profiling identifies novel molecular targets of paclitaxel and phytoagent deoxyelephantopin against mammary adenocarcinoma cells
Journal of Proteome Research
論文著作 (2010)
Comparative metabolomics approach coupled with cell- and gene-based assays for species classification and anti-inflammatory bioactivity validation of Echinacea plants
Journal of Nutritional Biochemistry
論文著作 (2009)
Use of Anoectochilus formosanus plant extracts and their derived fractions as herbal medicines or nutraceutical supplements for tumor prevention/treatment
PRC patent issued No. CN ZL03158682. 1
論文著作 (2009)
Use of Anoectochilus formosanus plant extracts and their derived fractions as herbal medicines or nutraceutical supplements for tumor prevention/treatment
Australia patent issued No. AU 2003244587
論文著作 (2009)
Truncated glucanase with enhanced activity and method for making the same
(US patent issued No. 7037696) (ROC patent issued No. 201683) (Two technology licensing/transfer to local biotech companies)
論文著作 (2009)
Truncated 1,3-1,4-beta- D-glucanase
US patent issued No. 7,527,958
論文著作 (2009)
Structural and catalytic roles of residues located in beta-13 strand and the following beta-turn loop in Fibrobacter succinogenes 1,3-1,4-beta-D-glucanase
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
論文著作 (2009)
Cancer and inflammatory disorder treatment
S patent issued No. 7547455 and ROC patents pending
論文著作 (2008)
Pure compounds (2-D-glucopyranosyloxy-1-hydroxytrideca-5,7,9,11-triyne and 3-D- glucopyranosyloxy-1-hydroxy-6(E)-tetradecene-8,10,12-triyne) and n-butanol fraction from Bidens pilosa Linn var radiate can prevent Th1-mediated autoimmune disease via suppressing Th1 cell differentiation and/or promoting Th2 cell differentiation
(US and ROC patents pending) (One technology licensing/transfer to local biotech company)
論文著作 (2008)
Immunomodulatory phytocompounds and the highly efficient platform to screen the same
US patent pending
論文著作 (2008)
Mutational and structural studies of the active-site residues in truncated Fibrobacter succinogenes 1,3–1,4-β-D-glucanase
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
論文著作 (2008)
Methods for enhancing proliferation of bone marrow cells or spleen cells with an ethanol-insoluble extract of Dioscorea
(US patent issued No: 7,419,690 B2; ROC patent pending) (One technology licensing/transfer to local biotech company)
論文著作 (2008)
Metabolomics for phytomedicine research and drug development
CURRENT OPINION IN CHEMICAL BIOLOGY
論文著作 (2008)
Hepatoprotective phytocompounds from Cryptomeria japonica are potent modulators of inflammatory mediators
PHYTOCHEMISTRY
論文著作 (2008)
Genomics and proteomics of immune modulatory effects of a butanol fraction of Echinacea purpurea in human dendritic cells
BMC Genomics
論文著作 (2008)
Effect of phytocompounds from the heartwood of Acacia confusa on inflammatory mediator production
Journal of Agricultural and Food Chemistry
論文著作 (2008)
A novel diterpene suppresses CWR22Rv1 tumor growth in vivo through antiproliferation and proapoptosis
Cancer Research
論文著作 (2008)
Immunomodulatory effects of phytocompounds characterized by in vivo transgenic human GM-CSF promoter activity in skin tissues
Journal of Biomedical Science
論文著作 (2008)
Structural modeling of glucanasesubstrate complexes reveals residue Tyr177 in barley 1,3-1,4-beta-D-glucanase plays an important role in carbohydrate recognition
Journal of Computer-Aided Molecular Design
論文著作 (2007)
Specific terpenoids and lignoids possess antiviral activities against SARS coronavirus
Journal of Medicinal Chemistry
論文著作 (2007)
Specific plant terpenoids and lignoids possess antiviral activities against SARS coronavirus
Journal of Medicinal Chemistry
論文著作 (2007)
Flavonoids, centaurein and centaureidin, from Bidens pilosa, stimulate IFN-gamma expression
Journal of Ethnopharmacology
論文著作 (2007)
Effects of Chamaecyparis formosensis Matasumura extractives on lipopolysaccharide-induced release of nitric oxide
Phytomedicine
論文著作 (2007)
Cytopiloyne, a novel polyacetylenic glucoside from Bidens pilosa, functions as a T helper cell modulator
Journal of Ethnopharmacology
論文著作 (2007)
A galactolipid possesses novel cancer chemopreventive effects by suppressing inflammatory mediators and mouse B16 melanoma
Cancer Research
論文著作 (2007)
A novel polyacetylene significantly inhibits angiogenesis and promotes apoptosis in human endothelial cells through activation of the CDK inhibitors and caspase-7
Planta Medica
論文著作 (2006)
Use of Anoectochilus formosanus plant extracts and their derived fractions as herbal medicines or nutraceutical supplements for chemoprevention or treatment of human malignancies
(US patent issued No. 7033617; Singapore patent issued No. 120937; PRC patent issued No. CN ZL03158682. 1) (One technology licensing/transfer to local biotech company)
論文著作 (2006)
Modulatory effects of Echinacea purpurea extracts on human dendritic cells: A cell- and gene-based study
Genomics
論文著作 (2005)
The distinct effects of a butanol fraction of Bidens pilosa plant extract on the development of Th1-mediated diabetes and Th2-mediated airway inflammation in mice
Journal of Biomedical Science
論文著作 (2005)
The distinct effects of a butanol fraction of Bidens pilosa extract on the development of Th1-mediated diabetes and Th2-mediated airway inflammation in mice
Journal of Biomedical Science
論文著作 (2005)
The distinct effects of a butanol fraction of Bidens pilosa extract on the development of Th1-mediated diabetes and Th2-mediated airway inflammation in mice
Journal of Biomedical Science
論文著作 (2005)
Phenolic antioxidants from the heatwood of Acacia confusa
Journal of Agricultural and Food Chemistry
論文著作 (2005)
Phenolic Antioxidants From the Heartwood of Acacia confusa
Journal of Agricultural and Food Chemistry
論文著作 (2005)
Ethyl caffeate suppresses NF-B activation and its downstream inflammatory mediators, iNOS, COX-2, and PGE2 in vitro or in mouse skin
British Journal of Pharmacology
論文著作 (2005)
Ethyl caffeate suppress NF B activation and its downstream inflammatory mediators, iNOS, COX-2 and PGE2 in vitro or in mouse skin
British Journal of Pharmacology
論文著作 (2005)
Crystal structure of truncated Fibrobacter succinogenes 1,3-1,4-beta-D-glucanase in complex with beta-1,3-1,4-cellotriose
J Mol Biol
論文著作 (2005)
Crystal structure of truncated Fibrobacter succinogenes 1,3-1,4-1-D-glucanase in complex with -1,3-1,4-cellotriose
J. Mol. Biol.
論文著作 (2005)
Chemical composition of the wood essential oil of Chamaecyparis formosensis Matsum and its antifungal activity
Holzforschung
論文著作 (2005)
Chemical composition of the wood essential oil of Chamaecyparis formosensis Matsum and its antifungal activity
Holzforschung
論文著作 (2005)
A truncated Fibrobacter succinogenes 1,3-1,4-beta-d-glucanase with improved enzymatic activity and thermotolerance
Biochemistry
論文著作 (2005)
A truncated Fibrobacter succinogenes 1,3-1,4-beta-d-glucanase with improved enzymatic activity and thermotolerance
Biochemistry
論文著作 (2005)
A 1,3-1,4-beta-D-glucanase from Fibrobacter succinogenes with improved enzymatic activity and thermotolerance
Biochemistry
論文著作 (2004)
Shikonins, phytocompounds from Lithospermum erythrorhizon, inhibit the transcriptional activation of human tumor necrosis factor alpha promoter in vivo
Journal of Biological Chemistry
論文著作 (2004)
Shikonin, hytocompounds from Lithospermum erythrorhizon, inhibit the transcriptional activation of human tumor necrosis factor
Journal of Biological Chemistry
論文著作 (2004)
Polyacetylenic compounds and butanol fraction from Bidens pilosa can modulate the differentiation of helper T cells and prevent autoimmune diabetes in non-obese diabetic mice
Planta Medica
論文著作 (2004)
Polyacetylenic compound and butanol fraction from Bidens pilosa Linn can modulate the differentiation of helper T cells and prevent autoimmune diabetes in nonobese diabetes mice
Planta Medica
論文著作 (2004)
Polyacetylenic compound and butanol fraction from Bidens pilosa Linn can modulate the differentiation of helper T cells and prevent autoimmune diabetes in nonobese diabetes mice
Planta Medica
論文著作 (2004)
Polyacetylenes function as anti-angiogenic agents
PHARMACOLOGICAL RESEARCH
論文著作 (2004)
Polyacetylenes function as anti-angiogenic agents
Pharmaceutical Research
論文著作 (2004)
Metabolite profiling and chemopreventive bioactivity of plant extracts from Bidens pilosa
Journal of Ethnopharmacology
論文著作 (2004)
Metabolite Profiling and Chemopreventive Bioactivity of Plant Extracts from Bidens pilosa
Journal of Ethnopharmacology
論文著作 (2004)
Medicinal herb extract and a single-compound drug confer similar complex pharmacogenomic activities in MCF-7 cells
Journal of Biomedical Science
論文著作 (2004)
Induction of specific apoptotic pathways in MCF-7 cells by phytochemicals from medicinal herb Anoectochilus formosanus
Journal of Biomedical Science
論文著作 (2004)
Induction of apoptosis in MCF-7 human breast cancer cells by phytochemicals from Anoectochilus formosanus
J. Biomed. Sci.
論文著作 (2004)
Antioxidant activity of extracts from Calocedrus formosana leaf, bark and heartwood
Journal of Wood Science
論文著作 (2004)
Antioxidant Activity of Extracts from Calocedrus formosana Leaf, Bark and Heartwood
JOURNAL OF WOOD SCIENCE
論文著作 (2003)
Tissue Array Transgene Expression System for the Evaluation of Effect of Medicinal Herbs on Wound-healing
J. Genet. Mol. Biol.
論文著作 (2003)
Tissue array transgene expression system for the evaluation of effect of medicinal herbs on wound-healing
J Genet Mol Biol
論文著作 (2003)
Shikonins, phytocompounds from Lithospermum erythrorhizon, inhibit the transcriptional activation of human tumor necrosis factor alpha promoter in vivo
Journal of Biological Chemistry
論文著作 (2003)
Crystal structure of a natural circularly-permutated jellyroll protein: 1,3-1,4-b-D-glucanase from Fibrobacter succinogenes
JOURNAL OF MOLECULAR BIOLOGY
論文著作 (2003)
Antioxidant properties and phytochemical characteristics of extracts from Lactuca indica
Journal of Agricultural and Food Chemistry
論文著作 (2002)
Profiling and characterization of antioxidant activities in Anoectochilus formosanus Hayata
Journal of Agricultural and Food Chemistry
論文著作 (2002)
Mutagenesis of Trp(54) and Trp(203) residues on Fibrobacter succinogenes 1,3-1,4-beta-D-glucanase significantly affects catalytic activities of the enzyme
Biochemistry
論文著作 (2001)
Directed mutagenesis of specific active site residues on Fibrobacter succinogenes 1,3-1,4-b-D-glucanase significantly affects catalysis and enzyme structural stability
Journal of Biological Chemistry
論文著作 (2001)
Crystallization of the 1,3-1,4-b-D-glucanase from Fibrobacter succinogenes
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
論文著作 (2001)
Antioxidant activity of extracts from Acacia confusa bark and heartwood
Journal of Agricultural and Food Chemistry
論文著作 (2001)
Antioxidant Activity of Abietane-Type Diterpenes from Heartwood of Taiwania cryptomerioides Hayata
Holzforschung
重要特殊獎項 (2020-05)
榮獲科技部2020年生命科學領域最具影響力專書 (編輯委員) “Medicinal Plants and Fungi -Recent Advances in Research and Development”, Co-editors
論文著作 (2021)
Phytogalactolipid dLGG inhibits mouse melanoma brain metastasis through regulating oxylipin activity and re-programming macrophage polarity in the tumor microenvironment
Cancers
論文著作 (2021)
Current advancements of plant-derived agents for triple-negative breast cancer therapy through deregulating cancer cell functions and reprogramming tumor microenvironment
International Journal of Molecular Sciences
論文著作 (2021)
Sesquiterpene lactone deoxyelephantopin isolated from Elephantopus scaber and its derivative DETD-35 suppress BRAFV600E mutant melanoma lung metastasis in mice
International Journal of Molecular Sciences
論文著作 (2021)
Extract of white sweet potato tuber against TNF-α-induced insulin resistant by activating the PI3K/Akt pathway in C2C12 myotubes
BOTANICAL STUDIES
論文著作 (2020)
White sweet potato ameliorates hyperglycemia and regenerates pancreatic islets in diabetic mice
Food & Nutrition Research
論文著作 (2020)
Transformation and characterization of 12-fatty acid acetylenase and 12-oleate desaturase potentially involved in the polyacetylene biosynthetic pathway from Bidens pilosa
Plants
論文著作 (2020)
Elucidation of enzymes involved in the biosynthetic pathway of bioactive polyacetylenes in Bidens pilosa using integrated omics approaches
Journal of Experimental Botany
論文著作 (2020)
Deregulating the CYP2C19/epoxyeicosatrienoic acid-associated FABP4/FABP5 signaling network as a therapeutic approach for metastatic triple negative breast cancer
Cancers
論文著作 (2020)
Association of arachidonic acid-derived lipid mediators with subsequent onset of acute myocardial infarction in patients with stable coronary artery disease
SCIENTIFIC REPORTS
論文著作 (2019)
Integrated omics-based pathway analyses uncover CYP epoxygenase-associated networks as theranostic targets for metastatic triple negative breast cancer
Journal of Experimental & Clinical Cancer Research
重要發現與突破 (2018)
植物半乳糖脂dLGG 藉由負調節TNF-α介導肺血管通透性與循環oxylipin的動態平衡來抑制黑色素瘤在小鼠體內的肺轉移
重要發現與突破 (2016)
有效抑制BRAF 突變及抗標靶藥 Vemurafenib黑色素腫瘤之新穎植物倍半萜內酯衍生物
重要發現與突破 (2016)
有效抑制BRAF 突變及抗標靶藥 Vemurafenib黑色素腫瘤之新穎植物倍半萜內酯衍生物
重要發現與突破 (2015)
降低膽固醇藥simvastatin與昭和草活性成分對治療動物敗血症之新穎功效與作用機制
重要發現與突破 (2012)
開發優質本土真菌漆化酵素用於生物復育及紙漿脫色
重要發現與突破 (2009)
地膽草之倍半萜成分具優良抑制乳癌的功能
重要發現與突破 (2009)
倍半萜化學成分 DET 與化療藥紫杉醇調控乳癌細胞之蛋白質體研究
重要發現與突破 (2007)
昭和草之癌症化學預防活性科學驗證與分子作用機制研究
重要特殊獎項 (2020)
National Innovation and Advancement Award, 2020 國家新創精進獎
重要特殊獎項 (2019-12-06)
The 16th National Innovation Award on Biopharmaceuticals and Precision Medicine, 2019 第十六屆國家新創獎
重要特殊獎項 (2019-12-06)
National Innovation and Advancement Award, 2019 國家新創精進獎
重要特殊獎項 (2018)
Tien-Der Lee Outstanding Biomedical Award, 2018 永信李天德卓越醫藥科技獎
重要特殊獎項 (2014)
National Invention and Creation Award, Invention Silver Award, 2014 國家創新發明獎
重要特殊獎項 (2013)
The 10th National Innovation Award on Agricultural Biotechnology, 2013 第十屆國家新創獎
重要特殊獎項 (2003)
Distinguished Young Investigator Award of Academia Sinica, 2003 年輕學者著作獎
專利
DUAL-FUNCTIONAL HYBRID GLUCANASES
USA-regular US9493751B2
徐麗芬
專利
新穎倍半?類化合物用於炎症與癌症之治療 Novel sesquiterpene derivatives and their use in inflammation or cancer treatment
Taiwan I535725
徐麗芬,李國雄,後藤(中川)享子,馮家華,陳若羽,李慧玲,鄭聿廷,黃菁盈
專利
USE of DEOXYELEPHANTOPIN (DET) AND ANALOGS THEREOF FOR TREATMENT OF MELANOMA USE of DEOXYELEPHANTOPIN (DET) AND ANALOGS THEREOF FOR TREATMENT OF MELANOMA
USA-regular US 9173868
徐麗芬
專利
USE OF DEOXYELEPHANTOPIN (DET) FOR TREATMENT OF MELANOMA
USA-regular US8754121B2
徐麗芬,趙文婉,鄭雅文,李淑華
專利
Novel Fungal Laccases and Uses Thereof
USA-regular US8728787
徐麗芬
專利
新穎真菌漆化酵素及其用途
Taiwan TW I 410492
徐麗芬
專利
高效率優質漆化酵素 Novel laccases from Lentinus sp.
USA-regular US8,492,131
徐麗芬
專利
免疫調節之組合物
Taiwan TW I 377347
楊文欽,張書林,江一民,徐麗芬
專利
免疫調節之組合物
Taiwan TW I 369497
楊文欽,張書林,江一民,徐麗芬
專利
BUTANOL EXTRACT OF BIDENS PILOSA
USA-regular US 8048860
徐麗芬,江一民,張書林,張力天,楊文欽
專利
Treatment of Cancer and Inflammatory Disorder Treatment of Cancer and Inflammatory Disorder
USA-regular US8048455
徐麗芬,侯珈禎,吳志鴻,陳奕平,王升陽,黃啟彰,楊寧蓀
專利
Use of Anoecttochilus formosanus plant extracts and their derived fractions as herbal medicine or nutraceutical supplements for chemoprevention or treatment of human malignancies
Indonesia ID P 0026520
徐麗芬
專利
具抗癌及抗發炎活性之萃取物及半乳糖脂之組合物
Taiwan I347192
徐麗芬,侯珈禎,王升陽,吳志鴻,陳奕平,黃啟彰,楊寧蓀
專利
咸豐草之正丁醇萃取物
Taiwan TW I 347191
楊文欽,張書林,徐麗芬,江一民,張力天
專利
山藥萃取物
Taiwan TW I 345471
楊寧蓀,徐麗芬,辛哈約克,蘇佩芬,李青晉
專利
Use of Anoecttochilus formosanus plant extracts and their derived fractions as herbal medicine or nutraceutical supplements for chemoprevention or treatment of human malignancies
Malaysia MY-142178-A
徐麗芬
專利
Immunomodulatory Compositions
USA-regular 7691575
楊文欽,張書林,江一民,徐麗芬
專利
Use of Anoecttochilus formosanus plant extracts and their derived fractions as herbal medicine or nutraceutical supplements for chemoprevention or treatment of human malignancies
Australia AU 2003244587
徐麗芬
專利
CANCER AND INFLAMMATORY DISORDER TREATMENT
USA-regular US7547455
徐麗芬,侯珈禎,王升陽,吳志鴻,陳奕平,黃啟彰,楊寧蓀
專利
Truncated 1, 3-1,4-b-d-glucanase
USA-regular 7527958
徐麗芬,陳瑞麟,楊寧蓀
專利
Use of Anoecttochilus formaosanus plant extracts and their derived fractions as herbal medicine or nutraceutical supplements for chemoprevention or treatment of human malignancies
China CN 100475753C
徐麗芬
專利
Dioscorea Extracts
USA-regular 7419690
楊寧蓀,徐麗芬,辛哈約克,蘇佩芬,李青晉
專利
利用金線連植物萃取 物為癌症預防(治療)之藥物或功能性食品
Singapore 120937
徐麗芬
專利
Truncated 1, 3-1,4-b-d-glucanase
USA-regular US 7,037,696 B1
徐麗芬,陳瑞麟,楊寧蓀
專利
Use of Anoectochilus Formosanus Plant Extracts and Their Derived Fractions as Herbal Medicines or Nutraceutical Supplements for Chemoprevention or Treatment of Human Malignancies
USA-regular US 7,033,617 B2
徐麗芬
專利
提高比活性及熱耐受性之截短型沙斯諾金纖維分解菌1,3-1,4-b-D-葡聚醣酵素
Taiwan 發明第201683號
徐麗芬,陳瑞麟,楊寧蓀
最新研究 (2021)
地膽草倍半萜內酯deoxyelephantopin及其衍生物 DETD-35 抑制BRAFV600E突變種黑色素瘤在小鼠體內之肺轉移
International Journal of Molecular Sciences, 2021, 22(6), 3226

中心訊息 2021-09-03
恭賀 徐麗芬特聘研究員與梁佑全研究副技師榮獲「2020國家新創精進獎」。

網站導覽 徐麗芬
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最新研究 (2)
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專利 (26)
論文著作 (119)
重要發現與突破 (8)
重要特殊獎項 (8)
網站導覽-選擇研究人員
葉國楨 楊玉良 葉信宏 施明哲 徐麗芬 邱子珍 常怡雍 楊文欽 蕭培文 詹明才 陳逸然 方素瓊 陳荷明 孫德芬 何承訓 劉明容 林耀正 山田昌史 林于鈴 林哲揚 吳岱娜 陳繪名 陳韻竹 林崇熙 辜瑞雪 梁佑全 董啟功 匡麟芸
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