Long noncoding RNA Smyca coactivates TGF-β/Smad and Myc pathways to drive tumor progression JOURNAL OF HEMATOLOGY & ONCOLOGY | |
Matriptase-2/NR4A3 axis switches TGF-β action toward suppression of prostate cancer cell invasion, tumor growth, and metastasis ONCOGENE | |
Blockage of glutamine-dependent anaplerosis affects mTORC1/2 activity and ultimately leads to cellular senescence-like response BIOLOGY OPEN | |
Necroptosis promotes autophagy-dependent upregulation of DAMP and results in immunosurveillance Autophagy | |
Transcriptomic analysis reveals a controlling mechanism for NLRP3 and IL-17A in dextran sulfate sodium (DSS)-induced colitis Scientific Reports | |
O-Glycosylation–mediated signaling circuit drives metastatic castration-resistant prostate cancer FASEB JOURNAL | |
The extracellular SEMA domain attenuates intracellular apoptotic signaling of semaphorin 6A in lung cancer cells Oncogenesis | |
A virus-like particle vaccination strategy expands its tolerance to H3N2 antigenic drift by enhancing neutralizing antibodies against hemagglutinin stalk Antiviral Research | |
A Standardized Wedelia chinensis extract overcomes the Feedback activation of HER2/3 signaling upon androgen-ablation in prostate cancer Frontiers in Pharmacology | |
A Standardized Wedelia chinensis extract mitigates tumor inflammation and augments chemotherapy effect of docetaxel in prostate cancer SCIENTIFIC REPORTS | |
Development of single-chain variable fragments (scFv) against influenza virus targeting hemagglutinin subunit 2 (HA2) Archives of Virology | |
A novel H6N1 virus-like particle vaccine induces long-lasting cross-clade antibody immunity against human and avian H6N1 viruses Antiviral Research | |
Induction of IL-25 secretion from tumour-associated fibroblasts suppresses mammary tumour metastasis Nature Communications | |
Immunogenicity of mammary tumor cells can be induced by shikonin via direct binding-interference with hnRNPA1 Oncotarget | |
Metastatic progression of prostate cancer is mediated by autonomous binding of galectin-4-O-glycan to cancer cells Cancer Research | |
Development of a standardized and effect-optimized herbal extract of Wedelia chinensis for prostate cancer Phytomedicine | |
Androgen-Induced TMPRSS2 Activates Matriptase and Promotes Extracellular Matrix Degradation, Prostate Cancer Cell Invasion, Tumor Growth, and Metastasis Cancer Research | |
Inactivated enterovirus 71 vaccine produced by 200-l scale serum-free microcarrier bioreactor system provides cross-protective efficacy in human SCARB2 transgenic mouse PLoS One | |
Shikonin-enhanced cell immunogenicity of tumor vaccine is mediated by the differential effects of DAMP components Molecular Cancer | |
Novel Cancer Therapeutics with Allosteric modulation of the mitochondrial c-Raf-DAPK complex by Raf inhibitor combination therapy Cancer Research | |
Rapamycin Promotes Mouse 4T1 Tumor Metastasis that Can Be Reversed by a Dendritic Cell-Based Vaccine PLoS One | |
Anticancer efficacy of unique pyridine-based tetraindoles European journal of medicinal chemistry | |
Rapid and sensitive early diagnosis of influenza virus subtype via surface enhanced Raman scattering J Biosens Bioelectron | |
The tetraindole SK228 reverses the epithelial-to-mesenchymal transition of breast cancer cells by up-regulating members of the miR-200 family PLoS ONE | |
Squalene-adjuvanted H7N9 virus vaccine induces robust humoral immune response against H7N9 and H7N7 viruses Vaccine | |
HAI-2 suppresses the invasive growth and metastasis of prostate cancer through regulation of matriptase ONCOGENE | |
Pharmacologic Down-regulation of EZH2 Suppresses Bladder Cancer in vitro and in vivo Oncotarget | |
Dietary uptake of Wedelia chinensis extract attenuates dextran sulfate sodium-induced colitis in mice PLoS One | |
Curcumin-targeting pericellular serine protease matriptase role in suppression of prostate cancer cell invasion, tumor growth and metastasis Cancer Prevention Research | |
Histone demethylase retinoblastoma binding protein-2 promotes lung tumorigenesis and cancer metastasis Cancer Research | |
A VLP Vaccine Induces broad-spectrum cross-protective antibody immunity against H5N1 and H1N1 subtypes of influenza a virus PLoS One | |
TET1 suppresses cancer invasion by activating the tissue inhibitors of metalloproteinases Cell Reports | |
A Cullin3-KLHL20 ubiqutin ligase-dependent pathway targets PML to amplify HIF-1 signaling and tumor hypoxia responses CANCER CELL | |
Mammalian expression of virus-like particles for advanced mimicry of authentic influenza virus PLoS One | |
Dual Degradation of Aurora A and B Kinases by the Histone Deacetylase Inhibitor LBH589 Induces G2-M Arrest and Apoptosis of Renal Cancer Cells CLINICAL CANCER RESEARCH | |
Herbal Extract of Wedelia chinensis Attenuates Androgen Receptor Activity and Orthotopic Growth of Prostate Cancer in Nude Mice CLINICAL CANCER RESEARCH | |
A novel diterpene suppresses CWR22Rv1 tumor growth in vivo through anti-proliferation and pro-apoptosis Cancer Research | |
Crucial Role of Estrogen Receptor-α Interaction with Transcription Coregulators in Follicle-StimulatingHormone and Transforming Growth Factor β1 Up-Regulation of Steroidogenesis in Rat Ovarian Granulosa Cells ENDOCRINOLOGY | |
Interplay of PI3K and cAMP/PKA signaling, and rapamycin-hypersensitivity in TGFß1 enhancement of FSH-stimulated steroidogenesis in rat ovarian granulosa cells JOURNAL OF ENDOCRINOLOGY | |
Critical involvement of ILK in TGFβ1-stimulated invasion/migration of human ovarian cancer cells is associated with urokinase plasminogen activator system Experimental Cell Research | |
Specific plant terpenoids and Ligands Possess potent antiviral activities against severe acute respiratory syndrome coronavirus Journal of Medicinal Chemistry | |
Diterpenes from Cryptomeria japonica Inhibit Androgen Receptor Transcriptional Activity in Prostate Cancer Cells Planta Medica | |
Compounds from Wedelia chinensis synergistically suppress androgen activity and growth in prostate cancer cells CARCINOGENESIS | |
Early detection of antibodies against various structural proteins of the SARS-associated coronavirus in SARS patients Journal of Biomedical Science | |
Characterization of two mosquito STATs, AaSTAT and CtSTAT: Differential regulation of tyrosine hosphorylation and DNA binding activity by LPS treatment and by Japanese encephalitis virus infection Journal of Biological Chemistry | |
BAF60a mediates critical interactions between nuclear receptors and the BRG1 chromatin-remodeling complex for transactivation MOLECULAR AND CELLULAR BIOLOGY | |
Chromatin remodeling and tissue-selective responses of nuclear hormone receptors BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE | |
Differential regulation of testosterone vs. 5 α-dihydrotestosterone by selective androgen response elements MOLECULAR AND CELLULAR BIOCHEMISTRY | |
The linkage of Kennedy's disease to Ran/ARA24, identified as the first androgen receptor poly-glutamine region associated coactivator Journal of Biological Chemistry | |
Isolation and characterization of ARA160 as the first androgen receptor N-terminal associated coactivator in human prostate cells Journal of Biological Chemistry | |
Increase in Akkermansiaceae in Gut Microbiota of Prostate Cancer-Bearing Mice International Journal of Molecular Sciences | |
CD28 engagement inhibits CD73-mediated regulatory activity of CD8+T cells Communications Biology | |
Comparison of Chicken Immune Responses after Inoculation with H5 Avian Influenza Virus-like Particles Produced by Insect Cells or Pupae JOURNAL OF VETERINARY RESEARCH | |
Arginine is an epigenetic regulator targeting TEAD4 to modulate OXPHOS in prostate cancer cells NATURE COMMUNICATIONS | |
Sesquiterpene Lactone Deoxyelephantopin Isolated from Elephantopus scaber and Its Derivative DETD-35 Suppress BRAF V600E Mutant Melanoma Lung Metastasis in Mice International Journal of Molecular Sciences | |
Sialyltransferase Inhibitors Suppress Breast Cancer Metastasis Journal of Medicinal Chemistry | |
Inhibition of TMPRSS2 by HAI-2 reduces prostate cancer cell invasion and metastasis ONCOGENE | |
Deregulating the CYP2C19/Epoxy-Eicosatrienoic Acid-Associated FABP4/FABP5 Signaling Network as a Therapeutic Approach for Metastatic Triple-Negative Breast Cancer Cancers | |
The mature EV71 virion induced a broadly cross-neutralizing VP1 antibody against subtypes of the EV71 virus PLOS ONE | |
O-鏈型醣化調節癌化信息驅動攝護腺癌產生轉移與荷爾蒙抗性 | |
黃花蜜菜標準化草藥調整攝護腺腫瘤發炎反應及改善克癌易化療的結果 | |
黃花蜜菜標準化草藥有效抑制攝護腺癌對荷爾療法產生抗性 | |
自主性galectin-4結合癌細胞表面的O型醣鏈造成攝護腺癌惡化轉移 | |
研發流感疫苗的尖端科技：利用哺乳動物細胞表現之類病毒顆粒模擬流感病毒 | |
黃花蜜菜天然抽出物抑制雄性素受體活性與前列腺腫瘤之原位生長 | |
新的二萜類化合物能藉由抑制雄性素受體、細胞增生與促細胞凋零達而致抗前列腺癌功效 | |
8th, National Innovation Award (Academic Research Group, Food Category) by Institute for Biotechnology and Medicine Industry on “Wedelia chinensis extract modulates prostate cancer, benign prostatic hyperplasia (BPH) and androgen-regulated disease”. | |
8th National Innovation Award (Academic Research Group, Pharmacy Category) by Institute for Biotechnology and Medicine Industry on "Applications of Mammalian-expressed Influenza Virus-like Particles (VLPs) for Vaccine/ Antibody Manufacture and Virus Diagn | |
The 2011 Academia Sinica Career Development Award | |
TRANSCRIPTION MODULATOR COMPOSITIONS USA-regular US 9144591 蕭培文 | |
產生類病毒微粒之高產率轉殖基因哺乳動物表現系統 Taiwan TWI 494430 蕭培文,吳佳穎,葉怡均 | |
High yield transgenic mammalian expression system for generating virus-like particles USA-regular US 8980281 蕭培文,吳佳穎,葉怡均 | |
二帖類化合物於治療攝護腺癌之用途 Taiwan TWI 434680 蕭培文,林楓閔,王升陽 | |
Transcription Modulator Compositions USA-regular US8,597,701 B2 蕭培文 | |
Use of diterpene,6-hydroxy-5,6-dehydrosugiol,and its derives in treatment of prostate cancer USA-regular US8519007 蕭培文,林楓閔,王升陽 | |
轉錄調控組合物 Taiwan TW I 405966 蕭培文 | |
Transcription Modulator Compositions China CN 101313926B 蕭培文 | |
產生類病毒微粒之高產率轉殖基因哺乳動物表現系統 Taiwan TW I 340166 蕭培文,楊寧蓀,黃銓珍,林恩豪 | |
轉錄調控物組合物 Taiwan TW I324521 蕭培文 | |
地膽草倍半萜內酯deoxyelephantopin及其衍生物 DETD-35 抑制BRAFV600E突變種黑色素瘤在小鼠體內之肺轉移 International Journal of Molecular Sciences, 2021, 22(6), 3226 |  |
Exploring the Tumor Immune Microenvironment (TIME) by Tissue-Based Biomarker Measurements 游舒涵博士 (國立臺灣大學生物科技研究所助理教授) 2021/08/09 11:00 AM Webex 線上演講 |
