Research
| Research (2023) miRNA-mediated mitochondrial dysfunction is involved in the anti-triple-negative breast cancer cell activity of phytosesquiterpene lactones. more Antioxidants & Redox Signaling, (DOI: 10.1089/ars.2021.0251) |  |
| Research (2022) Phyto-sesquiterpene lactones DET and DETD-35 induce ferroptosis in vemurafenib sensitive and resistant melanoma via GPX4 inhibition and metabolic reprogramming more Pharmacological Research, 178, 106148. (doi.org/10.1016/j.phrs.2022.106148) |  |
| Research (2021) Sesquiterpene Lactone Deoxyelephantopin Isolated from Elephantopus scaber and its Derivative DETD-35 Suppress BRAFV600E Mutant Melanoma Lung Metastasis in Mice more International Journal of Molecular Sciences, 22(6), 3226 |  |
| Research (2021) Sesquiterpene Lactone Deoxyelephantopin Isolated from Elephantopus scaber and its Derivative DETD-35 Suppress BRAFV600E Mutant Melanoma Lung Metastasis in Mice more International Journal of Molecular Sciences, 2021, 22(6), 3226 |  |
| Research (2020) Elucidation of enzymes involved in the biosynthetic pathway of bioactive polyacetylenes in Bidens pilosa using integrated omics and transgenic approaches more Journal of Experimental Botany |  |
| Research (2020) Deregulating the CYP2C19/epoxy-eicosatrienoic acid-associated FABP4/FABP5 signaling network as a therapeutic approach for metastatic triple-negative breast cancer more Cancers, 12(1):199 |  |
| Research (2019) Essential oil of Mentha aquatic var. Kenting Water Mint suppresses two-stage skin carcinogenesis accelerated by BRAF inhibitor vemurafenib more Molecules, 24, 2344 |  |
| Research (2019) Phyto-sesquiterpene lactone deoxyelephantopin and cisplatin synergistically suppress lung metastasis of B16 melanoma in mice with reduced nephrotoxicity more Phytomedicine, 56: 194–206 |  |
| Research (2019) Cumingianoside A, a phyto-triterpenoid saponin inhibits acquired BRAF inhibitor resistant melanoma growth via programmed cell death more Frontiers in Pharmacology |  |
| Research (2019) Integrated omics-based pathway analyses uncover CYP epoxygenase-associated networks as theranostic targets for metastatic triple negative breast cancer more J Exp Clin Cancer Res, 38(1):187 |  |
| Research (2018) Plant galactolipid dLGG suppresses lung metastasis of melanoma through deregulating TNF-α-mediated pulmonary vascular permeability and circulating oxylipin dynamics in mice more International Journal of Cancer, 143(12):3248-3261 |  |
| Research (2017) Phytoagent deoxyelephantopin derivative inhibits triple negative breast cancer cell activity by inducing oxidative stress-mediated paraptosis-like cell death more Oncotarget, 8:56942-56958 |  |
| Research (2016) Phytomedicine polypharmacology: Cancer therapy through modulating the tumor microenvironment and oxylipin dynamics more Pharmacology & Therapeutics, 162:58-68 |  |
| Research (2016) Novel sesquiterpene lactone analogues as potent anti-breast cancer agents more Molecular Oncology, 10(6):921-937 |  |
| Research (2016) A novel plant sesquiterpene lactone derivative DETD-35 suppresses BRAFV600E mutant melanoma growth and overcomes acquired vemurafenib resistance in mice more Molecular Cancer Therapeutics, 15(6):1163-1176 |  |
| Research (2013) Herbal Medicine and Acupuncture for Breast Cancer Palliative Care and Adjuvant Therapy (Review Article) more Evidence-Based Complementary and Alternative Medicine, Volume: 2013, Article ID 437948 |  |
| Research (2013) Phytoagents for cancer management: regulation of nucleic acid oxidation, ROS, and related mechanisms more Oxidative Medicine and Cellular Longevity |  |
| Research (2013) A plant kavalactone desmethoxyyangonin prevents inflammation and fulminant hepatitis in mice more PLOS ONE, Volume 8, Issue 10, e77626 |  |
| Research (2012) Deoxyelephantopin impedes mammary adenocarcinoma cell motility by inhibiting calpain-mediated adhesion dynamics and inducing reactive oxygen species and aggresome formation more Free Radical Biology & Medicine, 52 1423–1436 |  |
| Research (2012) Engineering of dual functional hybrid glucanases more Protein Engineering, Design and Selection, 25(11):771-780 |  |
| Research (2012) Biological Degradation of Anthroquinone and Azo Dyes by a Novel Laccase from Lentinus sp more Environmental Science and Technology, 46:5109-5117 |  |
| Research (2011) A sesquiterpenol extract potently suppresses inflammation in macrophages and mice skin and prevents chronic liver damage in mice through JNK-dependent HO-1 expression more Phytochemistry, 72(4-5):391-9 |  |
| Research (2010) Current Research and Development of Chemotherapeutic Agents for Melanoma more Cancers, 2: 397-419 |  |
| Research (2010) Deoxyelephantopin, a novel multifunctional agent, suppresses mammary tumor growth and lung metastasis and doubles survival time in mice more British Journal of Pharmacology, 159, 856-871 |  |
| Research (2010) Differential proteomic profiling identifies novel molecular targets of paclitaxel and phytoagent deoxyelephantopin against mammary adenocarcinoma cells more Journal of Proteome Research, 9, 237-253 |  |
| Research (2008) Metabolomics for phytomedicine research and drug development more Current Opinion in Chemical Biology, 12, 66-71 |  |
| Research (2008) Hepatoprotective phytocompounds from Cryptomeria japonica are potent modulators of inflammatory mediators more Phytochemistry, 69, 1348-1358 |  |
| Research (2007) Specific plant terpenoids and lignoids possess potent antiviral activities against SARS coronavirus more Journal of Medicinal Chemistry |  |
| Research (2007) A novel polyacetylene significantly inhibits angiogenesis and promotes apoptosis in human endothelial cells through activation of the CDK inhibitors and caspase-7 more Planta Medica |  |
| Research (2007) A galactolipid possesses novel cancer chemopreventive effects by suppressing inflammatory mediators and mouse B16 melanoma more Cancer Research, 67: 6907-6915 |  |
| Research (2006) Modulatory effects of Echinacea purpurea extracts on human dendritic cells: A cell- and gene-based study more Genomics | |
| Research (2006) Cytopiloyne, a novel polyacetylenic glucoside from Bidens pilosa, functions as a T helper cell modulator more J. Ethnopharmacology | |
| Research (2006) Modulatory effects of Echinacea purpurea extracts on human dendritic cells: A cell- and gene-based study more Genomics | |
| Research (2006) Truncated glucanase with enhanced activity and method for making the same more | |
| Research (2006) Use of Anoectochilus formosanus plant extracts and their derived fractions as herbal medicines or nutraceutical supplements for tumor prevention/ treatment more | |
| Research (2005) Use of Anoectochilus formosanus plant extracts and their derived fractions as herbal medicines or nutraceutical supplements for tumor prevention/ treatment more |  |
| Research (2005) Ethyl caffeate suppresses NF-kB activation and its downstream inflammatory mediators, iNOS, COX-2 and PGE2 in vitro or in mouse skin more British journal of pharmacology, 146: 352-363 |  |
| Research Cytopiloyne, a novel polyacetylenic glucoside from Bidens pilosa , functions as a T helper cell modulator more |  |
| Research Modulatory effects of Echinacea purpurea extracts on human dendritic cells: A cell- and gene-based study more | |
| Research Effect of phytocompounds from the heartwood of Acacia confusa on inflammatory mediator production more J. Agric. Food Chem., 56, 1567-1573 |  |
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— Lie-Fen Shyur
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| Research (40) |
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| Published Papers (120) |
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