Integrated proteomics and metabolomics reveal phytosesquiterpene lactones DET and DETD-35 inhibit triple-negative breast cancer cell activity by depleting ATP synthesis and reprogramming primary metabolism

Shiau, J.-Y., Huang, H.-J., Nakagawa-Goto, K., and Shyur, L.-F. * (2026) Integrated proteomics and metabolomics reveal phytosesquiterpene lactones DET and DETD-35 inhibit triple-negative breast cancer cell activity by depleting ATP synthesis and reprogramming primary metabolism Scientific Reports, 16: 5264