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ZINC TOLERANCE INDUCED BY IRON 1 reveals the importance of glutathione in the cross homeostasis between zinc and iron in Arabidopsis thaliana

ZINC TOLERANCE INDUCED BY IRON 1 reveals the importance of glutathione in the cross homeostasis between zinc and iron in Arabidopsis thaliana相片
ZINC TOLERANCE INDUCED BY IRON 1 reveals the importance of glutathione in the cross homeostasis between zinc and iron in Arabidopsis thaliana相片
我們在先前的研究中發現適量的鐵可增加阿拉伯芥抗過量鋅的能力(Shanmugam et al., 2011)。為了要了解其中機制，我們篩選失去此功能的突變株ZIR1。經由遺傳鑑定，我們得知ZIR1為glutathione合成路徑中酵素的基因產生突變，而造成γ-ECS活性降低，所以導致突變株zir中glutathione的量降低至野生株的15%。在低glutathione下，導致鐵運輸的缺失。由此研究中，我們認為glutathione在植物鋅、鐵恆定上扮演重要角色。

V. Shanmugam, M. Tsednee and K.-C. Yeh * (2012) Plant Journal, 69 (6): 1006-1017