2025

Tsai Yi-Ta, Liu En-Ting, Yang Ming-Hsin, Kao Chien Chang, Tzeng Sheue-Fen, Chen Yu-Chi, Hsiao Pei-Wen , Feng An-Chieh, Shieh Grace S., Tsai Mong-Hsun, Chen Shau-Kwaun, Chiu Yi-Lin, Chen Chin Li, Wu Sheng-Tang, Meng En, Tsai Wen-Chiuan, Chao Tai-Kuang, Sun Guang-Huan, Chang Sun-Yran, Hung Mien-Chie, Cha Tai-Lung*

MYADM Activates RhoA-Mediated Ameboid Migration to Drive Metastasis. Cancer Research , 85(21), 4099-4121

Tzeng Sheue-Fen, Yu Yi-Ru, Park Jaeoh, von Renesse Janusz, Hsiao Huey-Wen, Hsu Chen-Hsuan, Garnica Josep, Chen Jintian, Chiu Lu-Ting, Santol Jonas, Chen Tse-Yu, Chung Pei-Han, Kandalaft Lana E., Starlinger Patrick, Hsieh Rodney Cheng-En, Yu Ming-Chin, Hsiao Pei-Wen , Carmona Santiago J., Chen Hung-Kai, Meng Zhen, Lin Yun-Han, Zhou Jingying, Tsai Chin-Hsien*, Ho Ping-Chih*

PLT012, a Humanized CD36-Blocking Antibody, Is Effective for Unleashing Antitumor Immunity Against Liver Cancer and Liver Metastasis. Cancer Discovery , 15(8), 1676-1696

Lin Yuan-Chi, Chen Chung-Hsin, Lee Ming-Shyue, Lee Cheng-Fan, Hsiao Pei-Wen , Huang Hsiang-Po*, Pu Yeong-Shiau*

Metabolomics-Based Liquid Biopsy for Predicting Clinically Significant Prostate Cancer. Cancers , 17(23), 3815

2024

Ku Chia-Chi*, Lin Cheng-Yu, Yang Chin-Rur, Yang Yu-Chih, Chen Po-Ling, Lin Yi-Te, Wang Pei-Ru, Lee Min-Shi, Liang Shu-Mei, Hsiao Pei-Wen *

Vaccine optimization for highly pathogenic avian influenza: Assessment of antibody responses and protection for virus-like particle vaccines in chickens. Vaccine: X , 20, 100552

Chen Chung-Hsin, Huang Hsiang-Po, Chang Kai-Hsiung, Lee Ming-Shyue, Lee Cheng-Fan, Lin Chih-Yu, Lin Yuan Chi, Huang William J., Liao Chun-Hou, Yu Chih-Chin, Chung Shiu-Dong, Tsai Yao-Chou, Wu Chia-Chang, Ho Chen-Hsun, Hsiao Pei-Wen *, Pu Yeong-Shiau*

Predicting Clinically Significant Prostate Cancer Using Urine Metabolomics via Liquid Chromatography Mass Spectrometry. The World Journal of Men's Health , 42, e59

Wu Guan-James, Hsiao Pei-Wen

Assessment of Anti-Prostate Cancer Activity among Four Seaweeds, with Focus on Caulerpa lentillifera J.Agardh. Foods , 13(9), 1411

Tsai Han-En, Chen Chia-Ling, Chang Tzu-Ting, Fu Chih-Wei, Chen Wei-Chia, Perez Ser John Lynon P., Hsiao Pei-Wen , Tai Ming-Hong, Li Wen-Shan

Development of a Novel, Potent, and Selective Sialyltransferase Inhibitor for Suppressing Cancer Metastasis. International Journal of Molecular Sciences , 25(8), 4283

2023

Huang Hsiang-Po, Chen Chung-Hsin, Chang Kai-Hsiung, Lee Ming-Shyue, Lee Cheng-Fan, Chao Yen-Hsiang, Lu Shih-Yu, Wu Tzu-Fan, Liang Sung-Tzu, Lin Chih-Yu, Lin Yuan Chi, Liu Shih-Ping, Lu Yu-Chuan, Shun Chia-Tung, Huang William J., Lin Tzu-Ping, Ku Ming-Hsuan, Chung Hsiao-Jen, Chang Yen-Hwa, Liao Chun-Hou, Yu Chih-Chin, Chung Shiu-Dong, Tsai Yao-Chou, Wu Chia-Chang, Chen Kuan-Chou, Ho Chen-Hsun, Hsiao Pei-Wen *, Pu Yeong-Shiau*

Prediction of clinically significant prostate cancer through urine metabolomic signatures: A large-scale validated study. Journal of Translational Medicine , 21(1), 714

Wu Chia-Ying, Kao Shao-En, Tseng Yung-Chieh, Lin Yu-Po, Hou Jen-Tzu, Wu Li-Yang, Chiu Sharon, Ma Che Alex, Hsiao Pei-Wen , Hsiao Jane, Chen Juine-Ruey*

Pilot-scale production of inactivated monoglycosylated split H1N1 influenza virus vaccine provides cross-strain protection against influenza viruses. Antiviral Research , 216, 105640

Wang Jing-Ping, Hung Chun-Hao*, Liou Yae-Huei, Liu Ching-Chen, Yeh Kun-Hai, Wang Keh-Yang, Lai Zheng-Sheng, Chatterjee Biswanath, Hsu Tzu-Chi, Lee Tung-Liang, Shyu Yu-Chiau, Hsiao Pei-Wen , Chen Liuh-Yow, Chuang Trees-Juen, Yu Chen-Hsin Albert, Liao Nan-Shih, Shen C-K James*

Long-term hematopoietic transfer of the anti-cancer and lifespan-extending capabilities of a genetically engineered blood system by transplantation of bone marrow mononuclear cells. eLife , 12, RP88275

Tsai Chin-Hsien, Chuang Yu-Ming, Li Xiaoyun, Yu Yi-Ru, Tzeng Sheue-Fen, Teoh Shao Thing, Lindblad Katherine E., Di Matteo Mario, Cheng Wan-Chen, Hsueh Pei-Chun, Kao Kung-Chi, Imrichova Hana, Duan Likun, Gallart-Ayala Hector, Hsiao Pei-Wen , Mazzone Massimiliano, Ivanesevic Julijana, Liu Xiaojing, de Visser Karin E., Lujambio Amaia, Lunt Sophia Y., Kaech Susan M., Ho Ping-Chih*

Immunoediting instructs tumor metabolic reprogramming to support immune evasion. Cell Metabolism , 35(1), 118-133.e7

2022

Hsin-Yi Chen, Shu-Jou Chan, Xinxin Liu, An-Chi Wei, Ru-In Jian, Kuan-Wei Huang, Yaw-Dong Lang, Jou-Ho Shih, Chun-Chieh Liao, Chiu-Lin Luan, Yu-Tung Kao, Shang-Yin Chiang, ( Pei-Wen Hsiao ), Yuh-Shan Jou, Yunching Chen & Ruey-Hwa Chen*

Long noncoding RNA Smyca coactivates TGF-β/Smad and Myc pathways to drive tumor progression. JOURNAL OF HEMATOLOGY & ONCOLOGY , 15, 85

Hsin-Ying Lin, Chun-Jung Ko, Tzu-Yu Lo, Shang-Ru Wu, Shao-Wei Lan, Chen-An Huang, Yi-Chin Lin, Hsin-Hsien Lin, Hsin-Fang Tu, Cheng-Fan Lee, ( Pei-Wen Hsiao ), Hsiang-Po Huang, Mei-Jou Chen, Kai-Hsiung Chang & Ming-Shyue Lee*

Matriptase-2/NR4A3 axis switches TGF-β action toward suppression of prostate cancer cell invasion, tumor growth, and metastasis. ONCOGENE , 41, 2833-2845

2021

Pin-Yu Huang, Yu-Chih Yang, Chun-I Wang, Pei-Wen Hsiao , Hsin-I Chiang*, Ting-Wen Chen*

Increase in Akkermansiaceae in Gut Microbiota of Prostate Cancer-Bearing Mice. International Journal of Molecular Sciences , 22(17), 9626

Yo Ping Lai, Lu Cheng Kuo, Been Ren Lin, Hung Ju Lin, Chih Yu Lin, Yi Ting Chen, Pei Wen Hsiao , Huan Tsung Chang, Patrick Chow In Ko, Hsiao Chin Chen, Hsiang Yu Chang, Jean Lu, Hong Nerng Ho, Betty A. Wu-Hsieh, John T. Kung, Shu Ching Chen*

CD28 engagement inhibits CD73-mediated regulatory activity of CD8+T cells. Communications Biology , 4, 595

Dean Huang, Yu-Chan Chao, Zhengbing Lv, Jia-Tsrong Jan, Yu-Chih Yang, Pei-Wen Hsiao , Chia-Ying Wu, Chiu-Hsun Liao, Tzu-Hsien Wu, Lih-Chiann Wang*

Comparison of Chicken Immune Responses after Inoculation with H5 Avian Influenza Virus-like Particles Produced by Insect Cells or Pupae. JOURNAL OF VETERINARY RESEARCH , 65(2), 139-145

Chia-Lin Chen, Sheng-Chieh Hsu, Tan-Ya Chung, Cheng-Ying Chu, Hung-Jung Wang, Pei-Wen Hsiao , Shauh-Der Yeh, David K. Ann, Yun Yen, Hsing-Jien Kung*

Arginine is an epigenetic regulator targeting TEAD4 to modulate OXPHOS in prostate cancer cells. NATURE COMMUNICATIONS , 12, 2398

Biljana Cvetanova, Meng-Yi Li, Chung-Chih Yang, Pei-Wen Hsiao , Yu-Chih Yang, Jia-Hua Feng, Ya-Ching Shen, Kyoko Nakagawa-Goto, Kuo-Hsiung Lee, Lie-Fen Shyur*

Sesquiterpene Lactone Deoxyelephantopin Isolated from Elephantopus scaber and Its Derivative DETD-35 Suppress BRAF V600E Mutant Melanoma Lung Metastasis in Mice. International Journal of Molecular Sciences , 22(6), 3226

Chih-Wei Fu, Han-En Tsai, Wei-Sheng Chen, Tzu-Ting Chang, Chia-Ling Chen, Pei-Wen Hsiao , Wen-Shan Li*

Sialyltransferase Inhibitors Suppress Breast Cancer Metastasis. Journal of Medicinal Chemistry , 64(1), 527-542

2020

Chun-Jung Ko, Ting-Wei Hsu, Shang-Ru Wu, Shao-Wei Lan, Ting-Feng Hsiao, Hsin-Ying Lin, Hsin-Hsien Lin, Hsin-Fang Tu, Cheng-Fan Lee, Cheng-Chung Huang, Mei-Ju May Chen, Pei-Wen Hsiao , Hsiang-Po Huang, Ming-Shyue Lee*

Inhibition of TMPRSS2 by HAI-2 reduces prostate cancer cell invasion and metastasis. ONCOGENE , 39, 5950-5963

Maria Karmella Apaya , Pei-Wen Hsiao , Yu-Chih Yang Lie-Fen Shyur*

Deregulating the CYP2C19/Epoxy-Eicosatrienoic Acid-Associated FABP4/FABP5 Signaling Network as a Therapeutic Approach for Metastatic Triple-Negative Breast Cancer. Cancers , 12(1), 199

2019

Liao GY, Lee MT, Fan JJ, Hsiao PW , Lee CS, Su SY, Hwang JJ*, Ke FC*

Blockage of glutamine-dependent anaplerosis affects mTORC1/2 activity and ultimately leads to cellular senescence-like response. BIOLOGY OPEN , 8(5), bio038257

Wu CY, Yu SL, Chen YT, Chen YH, Hsiao PW , Chow YH*, Chen JR*

The mature EV71 virion induced a broadly cross-neutralizing VP1 antibody against subtypes of the EV71 virus. PLOS ONE , 14(1), e0210553

2018

Sheng-Yen Lin, Sung-Yuan Hsieh, Yi-Ting Fan, Wen-Chi Wei, Pei-Wen Hsiao , Dai-Hua Tsai, Tzong-Shoon Wu, and Ning-Sun Yang*

Necroptosis promotes autophagy-dependent upregulation of DAMP and results in immunosurveillance. Autophagy , 14(5), 778-795

Tien-Jen Lin, Shu-Yi Yin, Pei-Wen Hsiao , Ning-Sun Yang and I-Jen Wang*

Transcriptomic analysis reveals a controlling mechanism for NLRP3 and IL-17A in dextran sulfate sodium (DSS)-induced colitis. Scientific Reports , 8, 14927

Sheue-Fen Tzeng, Chin-Hsien Tsai, Tai-Kuang Chao, Yu-Ching Chou, Yu-Chih Yang, Mong-Hsun Tsai, Tai-Lung Cha, and Pei-Wen Hsiao *

O-Glycosylation–mediated signaling circuit drives metastatic castration-resistant prostate cancer. FASEB JOURNAL , 32, 6869-6882

Cheng-Ying Shen, Ya-Chu Chang, Li-Han Chen, Wen-Chun Lin, Yung-Hua Lee, Shu-Tsen Yeh, Hsin-Kuang Chen, Wentao Fang, Chung-Ping Hsu, Jang-Ming Lee, Tzu-Pin Lu, Pei-Wen Hsiao , Liang-Chuan Lai, Mong-Hsun Tsai* and Eric Y. Chuang*

The extracellular SEMA domain attenuates intracellular apoptotic signaling of semaphorin 6A in lung cancer cells. Oncogenesis , 7(12), 95

2017

Ji-Rong Yang, Chieh-Yu Cheng, Chih-Yuan Chen, Chao-Hua Lin, Chuan-Yi Kuo, Hsiang-Yi Huang, Fu-Ting Wu, Yu-Chih Yang, Chia-Ying Wu, Ming-Tsan Liu*, and Pei-Wen Hsiao *

A virus-like particle vaccination strategy expands its tolerance to H3N2 antigenic drift by enhancing neutralizing antibodies against hemagglutinin stalk. Antiviral Research , 140, 62-75

Chin-Hsien Tsai, Sheue-Fen Tzeng, Shih-Chuan Hsieh, Chia-Jui Tsai, Yu-Chih Yang, Mong-Hsun Tsai, and Pei-Wen Hsiao *

A Standardized Wedelia chinensis extract overcomes the Feedback activation of HER2/3 signaling upon androgen-ablation in prostate cancer. Frontiers in Pharmacology , 8, 721

Chin-Hsien Tsai, Sheue-Fen Tzeng, Shih-Chuan Hsieh, Yu-Chih Yang, Yi-Wen Hsiao, Mong-Hsun Tsai, and Pei-Wen Hsiao *.

A Standardized Wedelia chinensis extract mitigates tumor inflammation and augments chemotherapy effect of docetaxel in prostate cancer. SCIENTIFIC REPORTS , 7(1), 15624

2016

Li TW, Cheng SF, Tseng YT, Yang YC, Liu WC, Wang SC, Chou MJ, Lin YJ, Wang Y, Hsiao PW , Wu SC, Chang DK*

Development of single-chain variable fragments (scFv) against influenza virus targeting hemagglutinin subunit 2 (HA2). Archives of Virology , 161(1), 19-31

Yang JR, Chen CY, Kuo CY, Cheng CY, Lee MS, Cheng MC, Yang YC, Wu CY, Wu HS, Liu MT*, Hsiao PW *

A novel H6N1 virus-like particle vaccine induces long-lasting cross-clade antibody immunity against human and avian H6N1 viruses. Antiviral Research , 126, 8-17

Shu-Yi Yin, Feng-Yin Jian, Yung-Hsiang Chen, Shih-Chang Chien, Mao-Chih Hsieh, Pei-Wen Hsiao , Wen-Hwa Lee, Yueh-Hsiung Kuo* and Ning-Sun Yang*

Induction of IL-25 secretion from tumour-associated fibroblasts suppresses mammary tumour metastasis. Nature Communications , 7, 11311

Shu-Yi Yin, Thomas Efferth, Feng-Yin Jian, Yung-Hsiang Chen, Chia-I Liu3, Andrew H.J. Wang, Yet-Ran Chen, Pei-Wen Hsiao , Ning-Sun Yang*

Immunogenicity of mammary tumor cells can be induced by shikonin via direct binding-interference with hnRNPA1. Oncotarget , 7(28), 43629-43653

Chin-Hsien Tsai, Sheue-Fen Tzeng, Tai-Kuang Chao, Chia-Yun Tsai, Yu-Chih Yang, Ming-Ting Lee, Jiuan-Jiuan Hwang, Yu-Ching Chou, Mong-Hsun Tsai, Tai-Lung Cha and Pei-Wen Hsiao *

Metastatic progression of prostate cancer is mediated by autonomous binding of galectin-4-O-glycan to cancer cells. Cancer Research , 76 (19), 5756-5767

2015

Tsai CH, Tzeng SF, Hsieh SC, Lin CY, Tsai CJ, Yang YC, Hsiao JH, Tsai MH, Lee MT, and Hsiao PW *

Development of a standardized and effect-optimized herbal extract of Wedelia chinensis for prostate cancer. Phytomedicine , 22(3), 406-414

Ko CJ, Huang CC, Lin HY, Juan CP, Lan SW, Shyu HY, Wu SR, Hsiao PW , Huang HP, Shun CT, Lee MS*.

Androgen-Induced TMPRSS2 Activates Matriptase and Promotes Extracellular Matrix Degradation, Prostate Cancer Cell Invasion, Tumor Growth, and Metastasis. Cancer Research , 75(14), 2949-2960

Wu CY, Lin YW, Kuo CH, Liu WH, Tai HF, Pan CH, Chen YT, Hsiao PW , Chan CH, Chang CC, Liu CC, Chow YH, Chen JR*.

Inactivated enterovirus 71 vaccine produced by 200-l scale serum-free microcarrier bioreactor system provides cross-protective efficacy in human SCARB2 transgenic mouse. PLoS One , 10(8), e0136420

Lin TJ, Lin HT, Chang WT, Mitapalli S P, Hsiao PW , Yin SY, Yang NS*.

Shikonin-enhanced cell immunogenicity of tumor vaccine is mediated by the differential effects of DAMP components. Molecular Cancer , 14, 174

Tsai YT, Chuang MJ, Tang SH, Wu ST, Chen YC, Sun GH, Hsiao PW , Huang SM, Lee HJ, Yu CP, Ho JY, Lin HK, Chen MR, Lin CC, Chang SY, Lin VC, Yu DS, Cha TL*.

Novel Cancer Therapeutics with Allosteric modulation of the mitochondrial c-Raf-DAPK complex by Raf inhibitor combination therapy . Cancer Research , 75(17), 3568-3582

Lin TJ, Liang WM, Hsiao PW , M S P, Wei WC, Lin HT, Yin SY, Yang NS*.

Rapamycin Promotes Mouse 4T1 Tumor Metastasis that Can Be Reversed by a Dendritic Cell-Based Vaccine. PLoS One , 10(10), e0138335

Fu CW, Hsieh YJ, Chang TT, Chen CL, Yang CY, Liao A, Hsiao PW , Li WS*.

Anticancer efficacy of unique pyridine-based tetraindoles. European journal of medicinal chemistry , 104, 165-176

2014

Lin YJ, Wu CY, Li T, Hsiao PW and Chang DK*

Rapid and sensitive early diagnosis of influenza virus subtype via surface enhanced Raman scattering. J Biosens Bioelectron , 5, 150

Wang CH, Chen CL, More SV, Hsiao PW , Hung WC, Li WS.

The tetraindole SK228 reverses the epithelial-to-mesenchymal transition of breast cancer cells by up-regulating members of the miR-200 family. PLoS ONE , 9(6), e101088

Wu CY, Chang CY, Ma, HH, Wang CW, Chen YT, Hsiao PW , Chang CC, Chan CH, Liu CC, Chen JR*.

Squalene-adjuvanted H7N9 virus vaccine induces robust humoral immune response against H7N9 and H7N7 viruses. Vaccine , 32(35), 4485-4494

Tsai CH, Teng CH, Cheng TS, Tu YT, Wu SR, Shyu HY, Ko CJ , Lan SW, Huang HP, Johnson MD, Lin CY, Hsiao PW *, Lee MS*

HAI-2 suppresses the invasive growth and metastasis of prostate cancer through regulation of matriptase. ONCOGENE , 33(38), 4643-4652

Tang SH, Huang HS, Wu HU, Tsai YT, Chuang MJ, Yu CP, Huang SM, Sun GH, Chang SY, Hsiao PW , Yu DS, Cha, TL*

Pharmacologic Down-regulation of EZH2 Suppresses Bladder Cancer in vitro and in vivo. Oncotarget , 5(21), 10342-10355

2013

Huang YT, Wen CC, Chen YH, Huang WC, Huang LT, Lin WC, Arulselvan P, Liao JW, Lin SH, Hsiao PW , Kuo SC, Yang NS

Dietary uptake of Wedelia chinensis extract attenuates dextran sulfate sodium-induced colitis in mice. PLoS One , 8(5), e64152

Cheng TS, Chen WC, Lin YY, Tsai CH, Liao CI, Shyu HY, Ko CJ, Tzeng SF, Huang CY, Yang PC, Hsiao PW , and Lee MS*

Curcumin-targeting pericellular serine protease matriptase role in suppression of prostate cancer cell invasion, tumor growth and metastasis. Cancer Prevention Research , 6(5), 495-505

Teng YC, Lee CF, Li YS, Chen YR, Hsiao PW , Chan MY, Lin FM, Huang HD, Chen YT, Jeng YM, Hsu CH, Yan Q, Tsai MD and Juan LJ*

Histone demethylase retinoblastoma binding protein-2 promotes lung tumorigenesis and cancer metastasis. Cancer Research , 73(15), 4711-4721

2012

Wu CY, Yeh YC, Chan JT, Yang YC, Yang JR, Liu MT, Wu HS, Hsiao PW *

A VLP Vaccine Induces broad-spectrum cross-protective antibody immunity against H5N1 and H1N1 subtypes of influenza a virus. PLoS One , 7, e42363

Hsu CH, Peng KL, Kang ML, Chen YR, ChuCS, Yang YC, Tsai CH, Jeng YM, Chen YT, Lin FM, Huang HD, Lu YY, Teng Yching, Lin ST, Shen L, Lin RK, Lee SB, Hsu H M, Yu JC*, Hsiao PW * and Juan LJ *

TET1 suppresses cancer invasion by activating the tissue inhibitors of metalloproteinases. Cell Reports , 2(3), 568-579

2011

Yuan WC, Lee YR, Huang SF, Lin YM, Chen TY, Chung HC, Tsai CH, Chen HY, Chiang CT, Lai CK, Lu LT, Chen CH, Gu DL, Pu YS, Jou YS, Lu KP, Hsiao PW , Shih HM, and Chen RH*.

A Cullin3-KLHL20 ubiqutin ligase-dependent pathway targets PML to amplify HIF-1 signaling and tumor hypoxia responses. CANCER CELL , 20, 214-228

2010

Chia-Ying Wu, Yi-Chun Yeh, Yu-Chih Yang, Ching Chou, Ming-Tsan Liu, Ho-Sheng Wu, Jia-Tsrong Chan, Pei-Wen Hsiao *

Mammalian expression of virus-like particles for advanced mimicry of authentic influenza virus. PLoS One , e9784

2009

Tai-Lung Cha*, Mei-Jen Chuang, Sheng-Tang Wu, Guang-Huan Sun, Sun-Yran Chang, Dah-ShyongYu, Shih-Ming Huang, Steven Kuan-Hua Huan, Tse-Chou Cheng, Tzu-Ting Chen, Pao-Luo Fan, Pei-Wen Hsiao

Dual Degradation of Aurora A and B Kinases by the Histone Deacetylase Inhibitor LBH589 Induces G2-M Arrest and Apoptosis of Renal Cancer Cells. CLINICAL CANCER RESEARCH , 15(3), 840-850

Chin-Hsien Tsai, Feng-Min Lin, Yu-Chih Yang, Ming-Ting Lee, Tai-Lung Cha, Guan-James Wu, Shih-Chuan Hsieh, Pei-Wen Hsiao *

Herbal Extract of Wedelia chinensis Attenuates Androgen Receptor Activity and Orthotopic Growth of Prostate Cancer in Nude Mice. CLINICAL CANCER RESEARCH , 15, 5435-5444

2008

Feng-Min Lin, Chin-Hsien Tsai, Yu-Chih Yang, Wei-Chun Tu, Li-Ru Chen, Yun-Sa Liang,Sheng-Yang Wang, Lie-Fen Shyur, Shih-Chang Chien, Tai-Lung Cha, Pei-Wen Hsiao *

A novel diterpene suppresses CWR22Rv1 tumor growth in vivo through anti-proliferation and pro-apoptosis. Cancer Research , 68(16), 6634-6642

Yun-Ju Chen, Ming-Ting Lee, Hsiao-Chun Yao, Pei-Wen Hsiao , Ferng-Chun Ke*, Jiuan-Jiuan Hwang*

Crucial Role of Estrogen Receptor-α Interaction with Transcription Coregulators in Follicle-StimulatingHormone and Transforming Growth Factor β1 Up-Regulation of Steroidogenesis in Rat Ovarian Granulosa Cells. ENDOCRINOLOGY , 149(8), 4658-4668

2007

Yun-Ju Chen, Pei-Wen Hsiao , Ming-Ting Lee, J Ian Mason, Ferng-Chun Ke*, Jiuan-Jiuan Hwang*

Interplay of PI3K and cAMP/PKA signaling, and rapamycin-hypersensitivity in TGFß1 enhancement of FSH-stimulated steroidogenesis in rat ovarian granulosa cells . JOURNAL OF ENDOCRINOLOGY , 192, 405-419

Sui-Wen Lin, Ferng-Chun Ke, Pei-Wen Hsiao , Ping-Ping Lee, Ming-Ting Lee*, Jiuan-Jiuan Hwang*

Critical involvement of ILK in TGFβ1-stimulated invasion/migration of human ovarian cancer cells is associated with urokinase plasminogen activator system. Experimental Cell Research , 313, 602-613

Chih-Chun Wen, Yueh-Hsiung Kuo, Jia-Tsrong Jan, Po-Huang Liang, Sheng-Yang Wang, Hong-Gi Liu, Ching-Kuo Lee, Shang-Tzen Chang, Chih-Jung Kuo, Shoei-Sheng Lee, Chia-Chung Hou, Pei-Wen Hsiao , Shih-Chang Chien, Lie-Fen Shyur,* Ning-Sun Yang*

Specific plant terpenoids and Ligands Possess potent antiviral activities against severe acute respiratory syndrome coronavirus. Journal of Medicinal Chemistry , 50, 4087-4095

Wei-Chun Tu, Sheng-Yang Wang, Shih-Chang Chien, Feng-Min Lin, Li-Ru Chen, Chih-Yang Chiu, Pei-Wen Hsiao *

Diterpenes from Cryptomeria japonica Inhibit Androgen Receptor Transcriptional Activity in Prostate Cancer Cells. Planta Medica , 73, 1407-1409

Feng-Min Lin, Li-Ru Chen, En-Hau Lin, Ferng-Chun Ke, Hsin-Yi Chen, Meng-Jen Tsai, Pei-Wen Hsiao *

Compounds from Wedelia chinensis synergistically suppress androgen activity and growth in prostate cancer cells. CARCINOGENESIS , 28(12), 2521-2529

2004

Ho-sheng Wu, Yueh-chun Hsieh, Ih-jen Su, Ting-hsiang Lin, Shu-chun Chiu, Yu-Fen Hsu, Jih-Hui Lin, Mei-Ching Wang, Jeou-Yuan Chen, Pei-Wen Hsiao , Geen-Dong Chang, Andrew H J Wang, Hsien-Wei Ting, Chih-Ming Chou*, Chang-Jen Huang*

Early detection of antibodies against various structural proteins of the SARS-associated coronavirus in SARS patients. Journal of Biomedical Science , 11, 117-126

Chang-Chi Lin, Chih-Ming Chou, Ya-Li Hsu, Jih-Ching Lien, Yu-Ming Wang, Shui-Tsung Chen, Shu-Chuan Tsai, Pei-Wen Hsiao , Chang-Jen Huang*

Characterization of two mosquito STATs, AaSTAT and CtSTAT: Differential regulation of tyrosine hosphorylation and DNA binding activity by LPS treatment and by Japanese encephalitis virus infection. Journal of Biological Chemistry , 279, 3308-3317

2003

Pei-Wen Hsiao , Christy J. Fryer, Kevin W. Trotter, Weidong Wang, Trevor K Archer*

BAF60a mediates critical interactions between nuclear receptors and the BRG1 chromatin-remodeling complex for transactivation. MOLECULAR AND CELLULAR BIOLOGY , 23, 6210-6220

2002

P. W. Hsiao , B. J. Deroo and T. K. Archer

Chromatin remodeling and tissue-selective responses of nuclear hormone receptors. BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE , 80, 343-351

2000

P. W. Hsiao , D. L. Lin, T. Thin and C. S. Chang

Differential regulation of testosterone vs. 5 α-dihydrotestosterone by selective androgen response elements. MOLECULAR AND CELLULAR BIOCHEMISTRY , 206, 169-175

1999

P. W. Hsiao , D. L. Lin, R. Nakao and C. Chang

The linkage of Kennedy's disease to Ran/ARA24, identified as the first androgen receptor poly-glutamine region associated coactivator. Journal of Biological Chemistry , 274, 20229-20234

P. W. Hsiao and C. Chang

Isolation and characterization of ARA160 as the first androgen receptor N-terminal associated coactivator in human prostate cells. Journal of Biological Chemistry , 274, 22373-22379