Pure compounds (2-D-glucopyranosyloxy-1-hydroxytrideca-5,7,9,11-triyne and 3-D- glucopyranosyloxy-1-hydroxy-6(E)-tetradecene-8,10,12-triyne) and n-butanol fraction from Bidens pilosa Linn var radiate can prevent Th1-mediated autoimmune disease via suppressing Th1 cell differentiation and/or promoting Th2 cell differentiation


Yang, W.-C., Chang, S.-L., Chang, L.-T., Chiang, Y.-M., and Shyur, L.-F. (2008) Pure compounds (2-D-glucopyranosyloxy-1-hydroxytrideca-5,7,9,11-triyne and 3-D- glucopyranosyloxy-1-hydroxy-6(E)-tetradecene-8,10,12-triyne) and n-butanol fraction from Bidens pilosa Linn var radiate can prevent Th1-mediated autoimmune disease via suppressing Th1 cell differentiation and/or promoting Th2 cell differentiation (US and ROC patents pending) (One technology licensing/transfer to local biotech company),

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