Dr. Ho-Ming Chen is a plant computational biologist whose research explores how plants regulate gene expression to balance growth and defense. By mining large-scale biological data, her work aims to accelerate smart breeding strategies that support sustainable agriculture and global food security.
Our team seeks to translate molecular codes into next-generation crop solutions, enabling precision breeding for durable disease resistance with reduced growth–defense tradeoffs.
We investigate how gene expression is
shaped by copy number variation, fine-tuned at the post-transcriptional level,
and ultimately translated into plant disease resistance and growth phenotypes.
By integrating high-throughput sequencing of diverse RNA signals, whole-genome
variation analysis, computational biology, and precision genome editing, we
decode the regulatory mechanisms and phenotypic outcomes of gene expression and
apply these insights to the breeding of better crops.