2025
Natural Products Targeting Protein Disulfide Isomerases: New Frontiers for Diabetes, Cancer, and Coagulation. Food Frontiers
, 6(5), 2165-2181
2024
Crosstalk within Intestinal EpitheliumEnteroendocrine Cells and Paneth Cells: Key Communicators Among Intestinal Epi-thelial CellsAspects of Intestinal Absorption, Homeostasis, and Immunity, Biomedicine. BIOMEDICINE
Enhancing the color and stress tolerance of cherry shrimp (Neocaridina davidi var. red) using astaxanthin and Bidens Pilosa. PLOS ONE
Synergistic effect of inhibiting CHK2 and DNA replication on cancer cell growth. ELIFE
Transcriptomics and gut microbiome analysis of the edible herb Bidens pilosa as a functional feed additive to promote growth and metabolism in tilapia (Oreochromis spp.). BMC Genomics
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Transcriptomic Insights and the Development of Microsatellite Markers to Assess Genetic Diversity in the Broodstock Management of Litopenaeus stylirostris. Animals
, 14(11) 1685
Novel Experimental Mouse Model to Study the Pathogenesis and Therapy of Actinobacillus pleuropneumoniae Infection. Pathogens
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Functional and mechanistic studies of a phytogenic formulation, Shrimp Best, in growth performance and vibriosis in whiteleg shrimp. Scientific Reports
, 14(1)
2023
Phytochemistry, Pharmacology and Mode of Action of the Anti-Bacterial Artemisia Plants. Bioengineering
, 10(6), 633
Pharmacological and mechanistic study of PS1, a Pdia4 inhibitor, in β-cell pathogenesis and diabetes in db/db mice. Cellular and Molecular Life Sciences
, 80(4), 101
Early Life Exposure to C<sub>16</sub>-Ceramide Improves Learning and Short-Term Memory Behavior during Adulthood in Mice. ACS Chemical Neuroscience
, 14, 1369-1378
A Novel Phytogenic Formulation, EUBIO-BPSG, as a Promising One Health Approach to Replace Antibiotics and Promote Reproduction Performance in Laying Hens. Bioengineering
, 10(3), 346
2021
On-Site Diagnosis of Poultry Coccidiosis by a Miniature Mass Spectrometer and Machine Learning. ACS Agricultural Science & Technology
Functional and Mechanistic Studies of Two Anti-coccidial Herbs, Bidens pilosa and Artemisia indica. Planta Medica
Protein disulfide isomerase a4 promotes lung cancer development via the Stat3 pathway in stromal cells Clinical and Translational Medicine. Clinical and Translational Medicine
Glutamatergic Neurons Differentiated from Embryonic Stem Cells: An Investigation of Differentiation and Associated Diseases. International Journal of Molecular Sciences
, 22(9), 4592
Identification of Novel Biomarkers for Pre-diabetic Diagnosis Using a Combinational Approach. Frontiers in Endocrinology
, 12, 641336
Kansuinine A Ameliorates Atherosclerosis and Human Aortic Endothelial Cell Apoptosis by Inhibiting Reactive Oxygen Species Production and Suppressing IKKβ/IκBα/NF-κB Signaling. International Journal of Molecular Sciences
, 22(19), 10309
Pdia4 regulates β‐cell pathogenesis in diabetes: molecular mechanism and targeted therapy. EMBO Molecular Medicine
, 13(10), e11668
Sesamol Ameliorates Renal Injury-Mediated Atherosclerosis via Inhibition of Oxidative Stress/IKKα/p53. Antioxidants
, 10(10), 1519
2020
Bidens pilosa: Nutritional Value and Benefits for Metabolic Syndrome. eFood
Authentication, phytochemical characterization and anti-bacterial activity of twoArtemisiaspecies. Food Chemistry
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Toxicity study of Bidens pilosa in animals. Journal of Traditional and Complementary Medicine
, 10(2), 150-157
Phytochemicals as modulators of β-cells and immunity for the therapy of type 1 diabetes: Recent discoveries in pharmacological mechanisms and clinical potential. Pharmacological Research
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2019
Anti-coccidial properties and mechanisms of an edible herb, Bidens pilosa, and its active compounds for coccidiosis. Scientific Reports
, 9, 2896
Ginkgolide A Prevents the Amyloid-β-Induced Depolarization of Cortical Neurons. Journal of Agricultural and Food Chemistry
, 67(1), 81-89
2018
Glatiramer acetate enhances myeloid-derived suppressor cell function via recognition of paired Ig-like receptor B. JOURNAL OF IMMUNOLOGY
, 201(6), 1727-1734
2017
Cytotoxic property of Streptocaulon baumii extracts and their isolated compounds against different human cancer cell lines. Philippine Science Letters
, 10(2), 89-97
Protein disulfide isomerase a4 acts as a novel regulator of cancer growth through the procaspase pathway. Oncogene
, 36(39),5484-5496
2016
Inhibiting MDSC differentiation from bone marrow with phytochemical polyacetylenes drastically impairs tumor metastasis. Scientific Reports
, 6(1), 36663
Herbal remedies for coccidiosis control: A review of plants, compounds and anticoccidial actions. Evidence-Based Complementary and Alternative Medicine
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Field trial of medicinal plant, Bidens pilosa, against eimeriosis in broilers. Scientific reports
, 6, 24692
Cytopiloyne, a polyacetylenic glucoside from Bidens pilosa, acts as a novel anticandidal agent via regulation of macrophages. Journal of ethnopharmacology
, 184, 72-80
Bidens pilosa and its active compound inhibit adipogenesis and lipid accumulation via down-modulation of the C/EBP and PPARgamma pathways. Scientific reports
, 6, 24285
Beneficial effect of Bidens pilosa on body weight gain, food conversion ratio, gut bacteria and coccidiosis in chickens. PLoS One
, 11(1), e0146141
Data on the effect of Cytopiloyne against Listeria monocytogenes infection in mice. Data in Brief
, 7, 995-998
2015
Naturally Occurring Anthraquinones: Chemistry and Therapeutic Potential in Autoimmune Diabetes. Evidence-based Complementary and Alternative Medicine
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Mechanistic Study of the Phytocompound, 2-β-D-Glucopyranosyloxy-1-hydroxytrideca-5,7,9,11-tetrayne in Human T-Cell Acute Lymphocytic Leukemia Cells by Using Combined Differential Proteomics and Bioinformatics Approaches. Evidence-based Complementary and Alternative Medicine
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Complementary and Alternative Medicine for Diabetes 2014. EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE
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Effect of Bidens pilosa on infection and drug resistance of Eimeria in chickens. Research in veterinary science
, 98, 74-81
Mammalian target of rapamycin complex 2 (mTORC2) regulates LPS-induced expression of IL-12 and IL-23 in human dendritic cells. JOURNAL OF LEUKOCYTE BIOLOGY
, 97(6), 1071-1080
2014
Ceramide inhibits insulin-stimulated Akt phosphorylation through activation of Rheb/mTORC1/S6K signaling in skeletal muscle. Cellular Signalling
, 26(7), 1400-1408
Botanical, Pharmacological, Phytochemical, and Toxicological Aspects of the Antidiabetic Plant L. Evidence-Based Complementary and Alternative Medicine
, 2014, 698617
2013
Polarization and reprogramming of myeloid-derived suppressor cells. Journal of molecular cell biology
, 5(3), 207-209
Natural cures for type 1 diabetes: A review of phytochemicals, Biological actions, and clinical potential. Current Medicinal Chemistry
, 20(7), 899-907
Myeloid-Derived Suppressor Cells in Autoimmune Diabetes: Their Anti-diabetic Potential and Mechanism. Journal of Diabetes & Metabolism
, S12, 004
Morus alba and active compound oxyresveratrol exert anti-inflammatory activity via inhibition of leukocyte migration involving MEK/ERK signaling. BMC complementary and alternative medicine
, 13, 45
Herbal therapies for type 2 diabetes mellitus: chemistry, biology, and potential application of selected plants and compounds. Evidence-Based Complementary and Alternative Medicine
, 2013, 378657
Complementary and alternative medicine for diabetes. Evidence-Based Complementary and Alternative Medicine
, 2013, 831068
Botanical, Pharmacological, Phytochemical and Toxicological Aspects of the Anti-diabetic plant Bidens pilosa L. Evidence-based Complementary and Alternative Medicine
, 2013, 698617
Bidens pilosa L. (Asteraceae): Botanical Properties, Traditional Uses, Phytochemistry, and Pharmacology.. Evidence-Based Complementary and Alternative Medicine
, 2013, 340215
Anti-diabetic effect and mode of action of cytopiloyne. Evidence-Based Complementary and Alternative Medicine
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2012
Shikonin induces immunogenic cell death in tumor cells and enhances dendritic cell-based cancer vaccine. Cancer Immunology Immunotherapy
, 61(11), 1989-2002
Shikonin enhances efficacy of a gene-based cancer vaccine via induction of RANTES. Journal of Biomedical Science
, 19(1), 42
Exendin-4 improves resistance to Listeria monocytogenes infection in diabetic db/db mice. Journal of veterinary science
, 13(3), 245-252
Curcumin induces the apoptosis of human monocytic leukemia THP-1 cells via the activation of JNK/ERK Pathways. BMC complementary and alternative medicine
, 12, 22
Catenarin Prevents Type 1 Diabetes in Nonobese Diabetic Mice via Inhibition of Leukocyte Migration Involving the MEK6/p38 and MEK7/JNK Pathways. Evidence-Based Complementary and Alternative Medicine
, 2012, 982396
Catenarin prevents type 1 diabetes in non-obese diabetic mice via inhibition of leukocyte migration involving the MEK6/p38 and MEK7/JNK pathways. Evidence-Based Complementary and Alternative Medicine
, 982396
2011
Combined phytochemistry and chemotaxis assays for identification and mechanistic analysis of anti-inflammatory phytochemicals in Fallopia japonica. PloS one
, 6(11), e27480
2010
Anti-inflammatory properties of phenolic compounds and crude extract from Phorphyra dentata. Journal of Ethnopharmacology
, 128(1),123-130
Anti-hyperglycemic properties of crude extract and triterpenes from Poria cocos. Evidence-based Complementary and Alternative Medicine
, 2010, 1-8
Suppression of cell cycle progression by Jun dimerization protein 2 (JDP2) involves down-regulation of cyclin A2. ONCOGENE
, 29(47), 6245-6256
Myeloid-derived suppressor cells prevent type 1 diabetes in murine models. JOURNAL OF IMMUNOLOGY
, 185(10), 5828-5834
2009
Role of Cybr, a cytohesin binder and regulator, in CD4+ T-cell function and host immunity. MOLECULAR IMMUNOLOGY
, 46, 3218-3223
Anti-hyperglycemic effects and mechanism of Bidens pilosa water extract. Journal of Ethnopharmacology
, 122(2), 379-383
Anti-diabetic properties of three common Bidens pilosa variants in Taiwan. PHYTOCHEMISTRY
, 70(10), 1246-1254
2007
咸豐草的功效. 科學發展
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The effect of centaurein on interferon gamma expression and Listeria infection in mice. TOXICOLOGY AND APPLIED PHARMACOLOGY
, 219(1), 54-61
Flavonoids, centaurein and centaureidin, from Bidens pilosa, stimulate IFN-g expression. Journal of Ethnopharmacology
, 112, 232-236
Cytopiloyne, a Polyacetylenic Glucoside, Prevents Type 1 Diabetes in Non-obese Diabetic Mice. JOURNAL OF IMMUNOLOGY
, 178, 6984-6993
Cytopiloyne, a novel polyacetylenic glucoside from Bidens pilosa, functions as a T helper cell modulator. Journal of Ethnopharmacology
, 110, 532-538
2006
Modulatory effects of Echinacea purpurea extracts on human dendritic cells: a cell- and gene-based study. Genomics
, 88(6), 801-808
2005
The distinct effect of a butanol fraction of Bidens pilosa plant extract on the development of Th1-mediated diabetes and Th2-mediated airway inflammation in mice J Biomed Sci. Journal of Biomedical Science
, 12(1), 79-89
2004
The SH3 domain of Tec kinase is essential for its targeting to activated CD28 costimulatory molecule. EUROPEAN JOURNAL OF IMMUNOLOGY
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Polyacetylenic compound and butanol fraction from Bidens pilosa Linn can modulate the differentiation of helper T cells and prevent autoimmune diabetes in nonobese diabetes mice. Planta Medica
, 70, 1045-1051
2001
Tec kinase signaling in T cells is regulated by phosphatidylinositol 3-kinase and the Tec pleckstrin homology domain. JOURNAL OF IMMUNOLOGY
, 166, 387-395
2000
Tec kinases: a family with multiple roles in immunity. IMMUNITY
, 12, 373-382
Role of Tec kinase in nuclear factor of activated T cells signaling. INTERNATIONAL IMMUNOLOGY
, 12, 1547-1552
1999
The role of Tec protein-tyrosine kinase in T cell signaling. Journal of Biological Chemistry
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Tec kinase is involved in transcriptional regulation of IL-2 and IL-4 in the CD28 pathway. EUROPEAN JOURNAL OF IMMUNOLOGY
, 29, 1842-1849