Published Papers
| Published Papers (2025) Natural Products Targeting Protein Disulfide Isomerases: New Frontiers for Diabetes, Cancer, and Coagulation more Food Frontiers | |
| Published Papers (2024-12-03) Crosstalk within Intestinal EpitheliumEnteroendocrine Cells and Paneth Cells: Key Communicators Among Intestinal Epi-thelial CellsAspects of Intestinal Absorption, Homeostasis, and Immunity, Biomedicine more BIOMEDICINE | |
| Published Papers (2024-12-01) Enhancing the color and stress tolerance of cherry shrimp (Neocaridina davidi var. red) using astaxanthin and Bidens Pilosa more PLOS ONE | |
| Published Papers (2024-11-08) Synergistic effect of inhibiting CHK2 and DNA replication on cancer cell growth more ELIFE | |
| Published Papers (2024-08) Transcriptomics and gut microbiome analysis of the edible herb Bidens pilosa as a functional feed additive to promote growth and metabolism in tilapia (Oreochromis spp.) more BMC Genomics | |
| Published Papers (2024-06) Transcriptomic Insights and the Development of Microsatellite Markers to Assess Genetic Diversity in the Broodstock Management of Litopenaeus stylirostris more Animals | |
| Published Papers (2024-05) Novel Experimental Mouse Model to Study the Pathogenesis and Therapy of Actinobacillus pleuropneumoniae Infection more Pathogens | |
| Published Papers (2024-05) Functional and mechanistic studies of a phytogenic formulation, Shrimp Best, in growth performance and vibriosis in whiteleg shrimp more Scientific Reports | |
| Published Papers (2023) Phytochemistry, Pharmacology and Mode of Action of the Anti-Bacterial Artemisia Plants more Bioengineering | |
| Published Papers (2023) Pharmacological and mechanistic study of PS1, a Pdia4 inhibitor, in β-cell pathogenesis and diabetes in db/db mice more Cellular and Molecular Life Sciences | |
| Published Papers (2023) Early Life Exposure to C16-Ceramide Improves Learning and Short-Term Memory Behavior during Adulthood in Mice more ACS Chemical Neuroscience | |
| Published Papers (2023) A Novel Phytogenic Formulation, EUBIO-BPSG, as a Promising One Health Approach to Replace Antibiotics and Promote Reproduction Performance in Laying Hens more Bioengineering | |
| Published Papers (2021) On-Site Diagnosis of Poultry Coccidiosis by a Miniature Mass Spectrometer and Machine Learning more ACS Agricultural Science & Technology | |
| Published Papers (2021) Functional and Mechanistic Studies of Two Anti-coccidial Herbs, Bidens pilosa and Artemisia indica more Planta Medica | |
| Published Papers (2021) Protein disulfide isomerase a4 promotes lung cancer development via the Stat3 pathway in stromal cells Clinical and Translational Medicine more Clinical and Translational Medicine | |
| Published Papers (2021) Glutamatergic Neurons Differentiated from Embryonic Stem Cells: An Investigation of Differentiation and Associated Diseases more International Journal of Molecular Sciences | |
| Published Papers (2021) Identification of Novel Biomarkers for Pre-diabetic Diagnosis Using a Combinational Approach more Frontiers in Endocrinology | |
| Published Papers (2021) Kansuinine A Ameliorates Atherosclerosis and Human Aortic Endothelial Cell Apoptosis by Inhibiting Reactive Oxygen Species Production and Suppressing IKKβ/IκBα/NF-κB Signaling more International Journal of Molecular Sciences | |
| Published Papers (2021) Pdia4 regulates β‐cell pathogenesis in diabetes: molecular mechanism and targeted therapy more EMBO Molecular Medicine | |
| Published Papers (2021) Sesamol Ameliorates Renal Injury-Mediated Atherosclerosis via Inhibition of Oxidative Stress/IKKα/p53 more Antioxidants | |
| Published Papers (2020) Bidens pilosa: Nutritional Value and Benefits for Metabolic Syndrome more eFood | |
| Published Papers (2020) Authentication, phytochemical characterization and anti-bacterial activity of twoArtemisiaspecies more Food Chemistry | |
| Published Papers (2020) Toxicity study of Bidens pilosa in animals more Journal of Traditional and Complementary Medicine | |
| Published Papers (2020) Phytochemicals as modulators of β-cells and immunity for the therapy of type 1 diabetes: Recent discoveries in pharmacological mechanisms and clinical potential more Pharmacological Research | |
| Published Papers (2019) Anti-coccidial properties and mechanisms of an edible herb, Bidens pilosa, and its active compounds for coccidiosis more Scientific Reports | |
| Published Papers (2019) Ginkgolide A Prevents the Amyloid-β-Induced Depolarization of Cortical Neurons more Journal of Agricultural and Food Chemistry | |
| Published Papers (2018) Glatiramer acetate enhances myeloid-derived suppressor cell function via recognition of paired Ig-like receptor B more JOURNAL OF IMMUNOLOGY | |
| Published Papers (2017) Cytotoxic property of Streptocaulon baumii extracts and their isolated compounds against different human cancer cell lines more Philippine Science Letters | |
| Published Papers (2017) Protein disulfide isomerase a4 acts as a novel regulator of cancer growth through the procaspase pathway more Oncogene | |
| Published Papers (2016) Inhibiting MDSC differentiation from bone marrow with phytochemical polyacetylenes drastically impairs tumor metastasis more Scientific Reports | |
| Published Papers (2016) Herbal remedies for coccidiosis control: A review of plants, compounds and anticoccidial actions more Evidence-Based Complementary and Alternative Medicine | |
| Published Papers (2016) Field trial of medicinal plant, Bidens pilosa, against eimeriosis in broilers more Scientific reports | |
| Published Papers (2016) Cytopiloyne, a polyacetylenic glucoside from Bidens pilosa, acts as a novel anticandidal agent via regulation of macrophages more Journal of ethnopharmacology | |
| Published Papers (2016) Bidens pilosa and its active compound inhibit adipogenesis and lipid accumulation via down-modulation of the C/EBP and PPARgamma pathways more Scientific reports | |
| Published Papers (2016) Beneficial effect of Bidens pilosa on body weight gain, food conversion ratio, gut bacteria and coccidiosis in chickens more PLoS One | |
| Published Papers (2016) Data on the effect of Cytopiloyne against Listeria monocytogenes infection in mice more Data in Brief | |
| Published Papers (2015) Naturally Occurring Anthraquinones: Chemistry and Therapeutic Potential in Autoimmune Diabetes more Evidence-based Complementary and Alternative Medicine | |
| Published Papers (2015) Mechanistic Study of the Phytocompound, 2-β-D-Glucopyranosyloxy-1-hydroxytrideca-5,7,9,11-tetrayne in Human T-Cell Acute Lymphocytic Leukemia Cells by Using Combined Differential Proteomics and Bioinformatics Approaches more Evidence-based Complementary and Alternative Medicine | |
| Published Papers (2015) Complementary and Alternative Medicine for Diabetes 2014 more EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE | |
| Published Papers (2015) Effect of Bidens pilosa on infection and drug resistance of Eimeria in chickens more Research in veterinary science | |
| Published Papers (2015) Mammalian target of rapamycin complex 2 (mTORC2) regulates LPS-induced expression of IL-12 and IL-23 in human dendritic cells more JOURNAL OF LEUKOCYTE BIOLOGY | |
| Published Papers (2014) Ceramide inhibits insulin-stimulated Akt phosphorylation through activation of Rheb/mTORC1/S6K signaling in skeletal muscle more Cellular Signalling | |
| Published Papers (2014) Botanical, Pharmacological, Phytochemical, and Toxicological Aspects of the Antidiabetic Plant L more Evidence-Based Complementary and Alternative Medicine | |
| Published Papers (2013) Polarization and reprogramming of myeloid-derived suppressor cells more Journal of molecular cell biology | |
| Published Papers (2013) Natural cures for type 1 diabetes: A review of phytochemicals, Biological actions, and clinical potential more Current Medicinal Chemistry | |
| Published Papers (2013) Myeloid-Derived Suppressor Cells in Autoimmune Diabetes: Their Anti-diabetic Potential and Mechanism more Journal of Diabetes & Metabolism | |
| Published Papers (2013) Morus alba and active compound oxyresveratrol exert anti-inflammatory activity via inhibition of leukocyte migration involving MEK/ERK signaling more BMC complementary and alternative medicine | |
| Published Papers (2013) Herbal therapies for type 2 diabetes mellitus: chemistry, biology, and potential application of selected plants and compounds more Evidence-Based Complementary and Alternative Medicine | |
| Published Papers (2013) Complementary and alternative medicine for diabetes more Evidence-Based Complementary and Alternative Medicine | |
| Published Papers (2013) Botanical, Pharmacological, Phytochemical and Toxicological Aspects of the Anti-diabetic plant Bidens pilosa L more Evidence-based Complementary and Alternative Medicine | |
| Published Papers (2013) Bidens pilosa L. (Asteraceae): Botanical Properties, Traditional Uses, Phytochemistry, and Pharmacology. more Evidence-Based Complementary and Alternative Medicine | |
| Published Papers (2013) Anti-diabetic effect and mode of action of cytopiloyne more Evidence-Based Complementary and Alternative Medicine | |
| Published Papers (2012) Shikonin induces immunogenic cell death in tumor cells and enhances dendritic cell-based cancer vaccine more Cancer Immunology Immunotherapy | |
| Published Papers (2012) Shikonin enhances efficacy of a gene-based cancer vaccine via induction of RANTES more Journal of Biomedical Science | |
| Published Papers (2012) Exendin-4 improves resistance to Listeria monocytogenes infection in diabetic db/db mice more Journal of veterinary science | |
| Published Papers (2012) Curcumin induces the apoptosis of human monocytic leukemia THP-1 cells via the activation of JNK/ERK Pathways more BMC complementary and alternative medicine | |
| Published Papers (2012) Catenarin Prevents Type 1 Diabetes in Nonobese Diabetic Mice via Inhibition of Leukocyte Migration Involving the MEK6/p38 and MEK7/JNK Pathways more Evidence-Based Complementary and Alternative Medicine | |
| Published Papers (2012) Catenarin prevents type 1 diabetes in non-obese diabetic mice via inhibition of leukocyte migration involving the MEK6/p38 and MEK7/JNK pathways more Evidence-Based Complementary and Alternative Medicine | |
| Published Papers (2011) Combined phytochemistry and chemotaxis assays for identification and mechanistic analysis of anti-inflammatory phytochemicals in Fallopia japonica more PloS one | |
| Published Papers (2010) Anti-inflammatory properties of phenolic compounds and crude extract from Phorphyra dentata more Journal of Ethnopharmacology | |
| Published Papers (2010) Anti-hyperglycemic properties of crude extract and triterpenes from Poria cocos more Evidence-based Complementary and Alternative Medicine | |
| Published Papers (2010) Suppression of cell cycle progression by Jun dimerization protein 2 (JDP2) involves down-regulation of cyclin A2 more ONCOGENE | |
| Published Papers (2010) Myeloid-derived suppressor cells prevent type 1 diabetes in murine models more JOURNAL OF IMMUNOLOGY | |
| Published Papers (2009) Role of Cybr, a cytohesin binder and regulator, in CD4+ T-cell function and host immunity more MOLECULAR IMMUNOLOGY | |
| Published Papers (2009) Anti-hyperglycemic effects and mechanism of Bidens pilosa water extract more Journal of Ethnopharmacology | |
| Published Papers (2009) Anti-diabetic properties of three common Bidens pilosa variants in Taiwan more PHYTOCHEMISTRY | |
| Published Papers (2007) 咸豐草的功效 more 科學發展 | |
| Published Papers (2007) The effect of centaurein on interferon gamma expression and Listeria infection in mice more TOXICOLOGY AND APPLIED PHARMACOLOGY | |
| Published Papers (2007) Flavonoids, centaurein and centaureidin, from Bidens pilosa, stimulate IFN-g expression more Journal of Ethnopharmacology | |
| Published Papers (2007) Cytopiloyne, a Polyacetylenic Glucoside, Prevents Type 1 Diabetes in Non-obese Diabetic Mice more JOURNAL OF IMMUNOLOGY | |
| Published Papers (2007) Cytopiloyne, a novel polyacetylenic glucoside from Bidens pilosa, functions as a T helper cell modulator more Journal of Ethnopharmacology | |
| Published Papers (2006) Modulatory effects of Echinacea purpurea extracts on human dendritic cells: a cell- and gene-based study more Genomics | |
| Published Papers (2005) The distinct effect of a butanol fraction of Bidens pilosa plant extract on the development of Th1-mediated diabetes and Th2-mediated airway inflammation in mice J Biomed Sci more Journal of Biomedical Science | |
| Published Papers (2004) The SH3 domain of Tec kinase is essential for its targeting to activated CD28 costimulatory molecule more EUROPEAN JOURNAL OF IMMUNOLOGY | |
| Published Papers (2004) Polyacetylenic compound and butanol fraction from Bidens pilosa Linn can modulate the differentiation of helper T cells and prevent autoimmune diabetes in nonobese diabetes mice more Planta Medica | |
| Published Papers (2001) Tec kinase signaling in T cells is regulated by phosphatidylinositol 3-kinase and the Tec pleckstrin homology domain more JOURNAL OF IMMUNOLOGY | |
| Published Papers (2000) Tec kinases: a family with multiple roles in immunity more IMMUNITY | |
| Published Papers (2000) Role of Tec kinase in nuclear factor of activated T cells signaling more INTERNATIONAL IMMUNOLOGY | |
| Published Papers (1999) The role of Tec protein-tyrosine kinase in T cell signaling more Journal of Biological Chemistry | |
| Published Papers (1999) Tec kinase is involved in transcriptional regulation of IL-2 and IL-4 in the CD28 pathway more EUROPEAN JOURNAL OF IMMUNOLOGY |
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— Wen-Chin Yang
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| Research (1) |
| Issued Patents (16) |
| Published Papers (80) |
| Research Findings (8) |
| Honors and Awards to ABRC Scientists (20) |
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