Fibrillar fibronectin and uses thereof.

An isolated protein comprising an RGD motif and having a fibrillar structure, for use in medicine, is disclosed. The RGD-containing protein is preferably fibronectin, and may be used in the treatment of cancer, particularly kidney, breast, lung or ovarian cancer. The protein may induce cell death by modulating an Akt signaling pathway. The protein may also be used as an adjuvant.

 

Co-researchers:Huang CY, Liang SM, Liang CM.