An optimized procedure greatly improves EST vector contamination removal. BMC

Vector contamination remains a serious concern to the data quality in the public sequence database nowadays. Based on the results presented here, we feel that our modified procedure with SeqClean should be recommended to all researchers for the task of vector removal from EST or genomic sequences.
Pei-Wen Hsiao

Chen, Y. A., Lin, C. C., Wang, C. D., Wu, H. B. and Hwang, P.I (2007) An optimized procedure greatly improves EST vector contamination removal. BMC Genomics, 8:416