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Dr. Kuo-Chen Yeh
Exploring the molecular logic of plant–soil interactions
Dr. Kuo-Chen Yeh is a plant biologist whose research explores how plants maintainnutrient and metal balance under changing environmental conditions. His workintegrates molecular mechanisms with ecological and agricultural perspectives,focusing on root plasticity, metal homeostasis, and plant responses to environmentalstress. Through interdisciplinary approaches, his research aims to bridge fundamentalplant science with challenges in sustainable agriculture, food security, andenvironmental resilience.
We believe that understanding the fundamental biology of plant–soil interactions isessential for building sustainable agricultural systems.
Our laboratory investigates how plants sense, regulate, and maintain mineralnutrient and metal homeostasis in highly dynamic and often stressful soilenvironments. Using a mechanism-driven and cross-scale approach, weintegrate molecular genetics, root developmental biology, stress physiology,and environmental chemistry to uncover how plants coordinate nutrientacquisition, detoxification, and adaptation. Our research bridges fundamentalmechanisms with crop improvement, sustainable agriculture, andenvironmental resilience.
Research Directions
Our research focuses on how plants maintain mineral nutrient and metalhomeostasis under dynamic and often adverse soil environments. Becauseessential metal elements such as iron and zinc operate within a narrowphysiological window between deficiency and toxicity, plants have evolvedsophisticated regulatory systems to coordinate metal sensing, uptake,transport, chelation, detoxification, and long-distance signaling.
Metal Homeostasis and Nutrient Signaling
We investigate molecular mechanisms governing iron and zinc homeostasis,including regulation of metal transporters, metal chelators such asnicotianamine, ubiquitin-mediated protein turnover, and integration of redoxand chromatin-level signaling pathways. These studies provide mechanisticfoundations for biofortification and metal tolerance.
Root Plasticity under Environmental Stress
Using rice as a major crop system, we study how roots adapt to hypoxia, highiron availability, and fluctuating water regimes. Our work demonstrates thataerenchyma formation and iron plaque deposition are independentlyregulated by distinct carotenoid-derived hormonal pathways, reshapingclassical views of root stress physiology.
Emerging Metal ContaminantsWe pioneer research on technology-critical metals released fromsemiconductor industries, integrating plant physiology, metal speciation, andenvironmental chemistry to assess transformation, uptake, toxicity, and food-chain risks in agricultural systems.
Translational Applications
By bridging basic mechanisms with crop and environmental applications, ourresearch supports sustainable agriculture, water-efficient cultivation systems,and climate-resilient food production.
Join Us
We welcome students and researchers who are curious about plant biology,environmental science, and crop systems to join our laboratory.Our research focuses on understanding how plants sense, regulate, andmaintain mineral nutrient and metal homeostasis in complex and dynamic soilenvironments. We aim to connect fundamental discoveries in plant biologywith broader challenges in sustainable agriculture, environmental resilience,and food security.Our laboratory encourages open, critical thinking and interdisciplinaryexploration. By integrating approaches from molecular genetics, biochemistry,plant physiology, root biology, and environmental chemistry, we study howplants interact with their environment across molecular, cellular, andecosystem scales. Members of our laboratory receive rigorous scientifictraining and opportunities to participate in international collaborations andconferences. We aim to cultivate researchers who combine strongmechanistic understanding with the ability to address real-world challenges inagriculture and the environment.Members of our laboratory receive rigorous scientific training andopportunities to participate in international collaborations and conferences.We aim to cultivate researchers who combine strong mechanistic
understanding with the ability to address real-world challenges in agricultureand the environment.If you are interested in joining our laboratory, please contact us with your CVand a brief description of your research interests.