Lie-Fen Shyur

Lie-Fen Shyur

Distinguished Research Fellow

From sustainable agriculture of medicinal plants to natural medicine R&D

From sustainable agriculture of medicinal plants to natural medicine R&D

Issued Patents

Botanical supplement and method for preventing diseases, promoting growth and survival of an animal by using the same

Inventor
Shyur, L.-F.*, Liang, Y.-C.*, Lin, W.-Y., Chang, C.-T., and Chang, M.-T.
Patent Info
US and ROC patent pending

Phytogenic supplement and method for preventing diseases, promoting growth of poultry by using the same

Inventor
Shyur, L.-F.*, Lien, Y.-Y.*, Cheng, M.-C., Cheng, Y.-B., Nguyen, M.T.T., and Chang, M.-T.
Patent Info
US patent pending

Phytogenic additive and application thereof in promoting growth and combating coccidiosis and/or necrotic enteritis

Inventor
Shyur, L.-F.*, Lien, Y.-Y.*, Cheng, M.-C., Chen, S.-E., Wang, S.-Y., Chang, M.-T., and Chang, C.-T.
Patent Info
ROC patent pending; USP

Phytogenic additive and application thereof in promoting egg production and egg quality.

Inventor
Shyur, L.-F.*, Chen, S.-E.*, and Chang, M.-T.
Patent Info
US patent pending

Methods of treating or preventing infectious diseases in shrimps

Inventor
Shyur, L.-F.*, Nan, F.-H.*, Liao, Z.-H., Shiau, J.-Y., and Chang, M.-T.
Patent Info
US patent pending

Use of Crassocephalum rabens extract in the prevention and/or treatment of fatigue and/or depression

Inventor
Shyur, L.-F.*, Liang, Y.-C.*, Chen, Y.-H., Lin, C.-J., Chang, M.-T., and Yang, C.-C.
Patent Info
US patent issued

Adjuvant composition comprising Crassocephalum rabens extract.

Inventor
Lin, Y.-L.*, Shyur, L.-F., Lin, H.-H., and Chang, M.-T.
Patent Info
US patent pending

Use of Crassocephalum rabens extract in inducing humoral immune response

Inventor
Lin, Y.-L.*, Shyur. L.-F., Lin, H.-H., Wu, Y.-S., and Chang, M.-T.
Patent Info
TW patent issued I890316, 2025/07/11
Australian patent AU2024222591A1, 2025/08/28
European patent EP4665369A2, 2025/12/24
South Korea KR1020250166898A, 2025/11/28

Use of Crassocephalum rabens extract in the treatment of breast cancer.

Inventor
Shyur, L.-F.*, Apaya, K. M., and Chang, M.-T.
Patent Info
ROC patent issued
US Patent pending

Mint essential oils inhibit HRASA61L mutant keratinocyte activity and prevent skin carcinogenesis

Inventor
Shyur, L.-F.*, Chang, C.-T., and Chen, Y.
Patent Info
ROC patent issued I759633
US patent issued

Novel sesquiterpene derivatives and their use in inflammation or cancer treatment

Inventor
Shyur, L.-F.*, Lee, K.-H., Nakagawa-Goto, K., Feng, J.-H., Chen, J.-Y., Lee, W.-L., Cheng, Y.-T., and Huang, J.-Y.
Patent Info
US patent issued US10238631 B2, 2019
PCT patent issued EU3151829 B1, 2019
PRC patent issued CN107072981B, 2021

Galactolipids-enriched plant extracts and the uses thereof

Inventor
Shyur, L.-F.*, Feng, J.-H., and Apaya, K. M.
Patent Info
US patent issued US 10434132 B2, 2019
European patent issued EP 2 810 651 B1, 2019
PRC patent issued CN 104208114 B, 2018
Japan patent issued 6033255, 2016
ROC patent issued I558403, 2016

Novel sesquiterpene derivatives and compositions comprising the same for treating inflammation and/or neoplasm related disorders

Inventor
Shyur, L.-F.*, Lee, K.-H., Nakagawa-Goto, K., Feng, J.-H., Chen, J.-Y., Lee, W.-L., Cheng, Y.-T., and Huang, J.-Y
Patent Info
ROC patent issued I535725

Dual-functional hybrid glucanases

Inventor
Shyur, L.-F.* and Liu, W.-C.
Patent Info
US patent issued 9,493,751

Use of deoxyelephantopin (DET) and analogues thereof for reducing side effects of an anti-cancer agent.

Inventor
Shyur, L.-F.*, Chao, W.-W., and Cheng, Y.-W.
Patent Info
US patent issued 9173868