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演講訊息

Current challenges and recent advancements on the authentication and adulteration of olive oil (Co-sponsored by Agricultural Biotechnology Research Center & Institute of Biological Chemistry, Academia Sinica)

Auditorium A134, Agricultural Technology Building
2015/01/05 10:30 AM
Dr. Selina Wang (Research Director, UC Davis Olive Center, Robert Mondavi Institute for Wine and Food Science, University of California, Davis, USA)
Host: Dr. Lie-Fen Shyur and Dr. Chun-Hung Lin


Research projects at the National Research Institute of Chinese Medicine

Auditorium A134, Agricultural Technology Building
2015/01/12 10:30 AM
Dr. Yi-Tsau Huang, M.D. (Director, Department of Chinese Medicine and Pharmacy, Ministry of Health and Welfare & Director, National Research Institute of Chinese Medicine, Ministry of Health and Welfare)
Host: Ning-Sun Yang


The saga of tumor suppressor genes: from basic understanding to clinical application

Auditorium A134, Agricultural Technology Building
2015/01/19 10:30 AM
Dr. Wen-Hwa Lee (Chancellor, China Medical University, Taichung, Taiwan)
Host: Ning-Sun Yang


The Acute Hypoglycemic Effect of Guava Leaf Extract in vivo – Is it Quercetin

Conference Room A133, Agricultural Technology Building
2015/01/26 10:30 AM
Dr. Henry J. Tsai (Associate Professor, Department of Health and Nutrition Biotechnology, Asia University)
Host: Lie-Fen Shyur


Academic & Industry Collaboration: Pharma View

Auditorium A134, Agricultural Technology Building
2015/01/30 2:00 PM
Dr. Wenji Chen (Director, Worldwide Business Development, GlaxoSmithKline, Shanghai, China)
Host: Lie-Fen Shyur


Involvement of the chloroplast translocon protein Tic55 in dark-induced senescence of Arabidopsis thaliana (探討阿拉伯芥葉綠體內膜蛋白Tic55參與黑暗誘導老化的過程)

Conference Room A133, Agricultural Technology Building
2015/02/05 10:30 AM
Dr. Po-Hsuan Chou (Assistant Professor, Department of Life Sciences, Tzu-Chi University, Taiwan)
Host: Choun-Sea Lin


Toward an understanding of bacterial pathogenesis in plants

Auditorium A134, Agricultural Technology Building
2015/02/09 13:30
Dr. Sheng Yang He (University Distinguished Professor, Department of Energy Plant Research Laboratory, Howard Hughes Medical Institute, Gordon-Betty Moore Foundation, Michigan State University, East Lansing, USA)
Host: Hisn-Hung Yeh
Plant diseases caused by microbial pathogens are major problems in agriculture. Basic understanding of pathogenesis holds a key to the development of novel and sustainable strategies for long-term disease control. We have been using the Arabidopsis thaliana-Pseudomonas syringae pv. tomato (Pst) DC3000 pathosystem to uncover general principles that underlie plant susceptibility to bacterial pathogens in plants. Pst DC3000 is representative of a large number of bacterial pathogens that infect the above-ground parts (phyllosphere) of plants. During infection, this pathogen produces a battery of virulence factors to engage multiple host cell types (e.g., stomatal and mesophyll cells) and diverse host physical and chemical barriers. Its type III secretion system (T3SS) delivers about 30 “effector” proteins into the plant cell, whereas the phytotoxin coronatine mimics the active form of plant hormone jasmonate. Study of the molecular action of T3SS effectors and coronatine demonstrates the great utility of Pst DC3000 pathogenesis as a probe in the discovery of fundamental aspects of bacterial diseases, hormone signaling mechanisms, and stomatal immune function in plants. I will give an overview of our ongoing studies and a perspective of future research in this area.


Discover and Connect Cellular Signaling (ABRC-IPMB Joint Seminar)

Auditorium A134, Agricultural Technology Building
2015/02/26 10:00~12:00
Prof. Jen Sheen (Professor, Dept. of Molecular Biology, Massachusetts General Hospital; Dept. of Genetics - Harvard Medical School, USA; Academician, Academia Sinica)
Host: Erh-Min Lai


Innovation and safety of adjuvant research and development

Auditorium A134, Agricultural Technology Building
2015/03/09 3:30 PM
Dr. Ken Ishii (Immunology Frontier Research Center, Osaka University, Japan)
Host: Shu-Mei Liang
The word adjuvant has its origin from the Latin "adjuvare", meaning "to help". It is a general term for substances (factors) which are co-administered with a vaccine with the aim of increasing the effect (immunogenicity) of the vaccine. The research and development of adjuvants has a history of more than 80 years, and their actual mechanism was not immunologically understood for a long time, with a famous sarcastic remark "Immunologist's dirty little secret". Recent advance in Immunolgy; however, allowed the development of adjuvants through an innovative scientific approach, and there is fierce competition worldwide for the development of next-generation adjuvants. I would like to introduce and discuss about several adjuvants with their novel mechanisms, including a small compound as a potent DAMPs inducer to target certain innate immune mechanisms.
 On the other hand, however, adjuvants range widely in terms of origin and mode of action, and they may be the cause or underlying cause of vaccine toxicity, especially immunotoxicity. I will present our recent work that common particulate adjuvants can cause local but sustained inflammation and allergic responses via novel innate immune mechanisms and cell death.


Computational genomics in the era of big data biology: a case study of genome dynamics in HEK293 cell lines

Auditorium A134, Agricultural Technology Building
2015/04/09 10:00 AM
Dr. Yao-Cheng Lin (Staff Scientist, VIB Department of Plant Systems Biology, Ghent University, Belgium)
Host: Tzyy-Jen Chiou
Computational genomics is a technology driven, data intensive field and requires researchers from cross disciplinary background working together. With the advert of high throughput genomics, life scientists are starting to crunch, share, integrate and archive data on a daily basis as their counterparts in astronomy or high energy physics. In this talk, I will present my work alone the next generation sequencing technologies movement where we are able to sequence and assemble the genome from the yeast size P. pastoris to a 20Gbp conifer. Furthermore, there is a high demand for the high quality genome annotation from a newly sequenced organism. The unique splice sites in the marine haptophyte demonstrate the annotation quality does matter in understanding the biology of an organism. With the well annotated genomes in hand, we can move forward by comparing multiple sequenced genomes and identify novel signaling peptides in plants and fungi. To end this talk, I will present my recent work on analysing the HEK293 cell lineage. We sequenced six 293 cell lines to study the dynamics of this aneuploid genome in response to the cell biology manipulations that were used to generate common derivatives of 293 cells. We observed that copy number alteration detection could identify the genomic region that enabled 293 cell survival under selective conditions.


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