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演講訊息

Environmental Epigenetics for the Primary Prevention of Cancer

Auditorium A134, Agricultural Technology Building, Agricultural Biotechnology Research Center
2018/09/03 10:30 AM
Dr. Sophie A. Lelièvre (Professor of Basic Medical Sciences with courtesy appointment in Nutrition Science; coleader, Drug Discovery & Molecular Sensing NCI-designated Purdue Center for Cancer Research; Scientific Director, 3D Cell Culture Core (3D3C) Facility, Birck Nanotechnology Center, Discovery Park, Purdue University, USA)
Host: Lie-Fen Shyur
In order to understand how to reduce the risk for chronic diseases related to metabolic changes like cancers, we need to decipher how environmental detrimental factors such as pollutants and high fat/high sugar dietary components modify the cells and their microenvironment. Similarly, the search for bioactive compounds from medicinal plants and fungi that would help decrease cancer risk requires the study of their impact on mechanisms of cancer onset. The chemical modifications on DNA and histones constitute the epigenome that, at any given time, controls gene expression. Since cancer onset is fundamentally linked to an altered epigenome, it is essential that the investigations of deleterious and protective environmental factors focus on epigenetic pathways. I will present how organs-on-a-chip, the state-of-the-art in vitro models prepared with humans cells, play a central role in this endeavor and might provide population-specific answers regarding how to modulate cancer risk. Oxidative stress, a paramount mediator of cancer related to pollution, psychological stress and unhealthy diet will be used as an example of how we can build a multi-organs-on-a-chip screening system.


The Conventional and Unconventional
Autophagy Pathways in Regulation of
Hepatocellular Carcinoma and Diabetes
Mellitus

Auditorium A134, Agricultural Technology Building, Agricultural Biotechnology Research Center
2018/09/05 4:00 PM
Dr. Shan-Ying Wu (Postdoctoral Fellow, Department of Microbiology and Immunology, National Cheng Kung University)
Host: Wen-Chin Yang


Oxygenic photosynthesis beyond the red-edge of visible light: photoacclimation of cyanobacteria to far-red light and chlorophyll f synthesis

Conference Room A133, Agricultural Technology Building
2018/09/13 4:00 PM
Dr. Ming-Yang Ho (Postdoctoral Researcher, Pennsylvania State University, USA)
Host: Yee-yung Charng


From Data-Dependent to Data-Independent Acquisition: the approaches of quantitative proteomics to study plant biology

Auditorium A134, Agricultural Technology Building, Academia Sinica
2018/09/17 10:30 AM
Dr. Kai-Ting Fan (Dr.Yet-Ran Chen’s Lab)
Host: Dr. Yet-Ran Chen


An integrated approach for metabolic
engineering

Auditorium A134, Agricultural Technology Building, Agricultural Biotechnology Research Center
2018/09/25 10:00 AM
Dr. Jyun-Liang Lin (Postdoctoral Fellow, Department of Biochemistry, University of Wisconsin-Madison)
Host: Yu-Liang Yang


  

2018 SEMINAR

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