Hsiang-chin Liu†, Jörn Lämke†, Siou-ying Lin†, Meng-Ju Hung, Kuan-Ming Liu, Yee-yung Charng*, Isabel Bäurle* (2018) Distinct heat shock factors and chromatin modifications mediate the organ-autonomous transcriptional memory of heat stress. Plant J. https://doi.org/10.1111/tpj.13958
Plants can be primed by a stress cue to mount a faster or stronger activation of defense mechanisms upon a subsequent stress. A crucial component of such stress priming is the modified reactivation of genes upon recurring stress; however, the underlying mechanisms are poorly understood. Here, we report that dozens of Arabidopsis thaliana genes display transcriptional memory, i.e. stronger upregulation after a recurring heat stress, that lasts for at least three days. We define a set of transcription factors involved in this memory response and show that the transcriptional memory results in enhanced transcriptional activation within minutes after the onset of a heat stress cue. Further, we show that the transcriptional memory is active in all tissues. It may last for up to a week, and is associated with histone H3 lysine 4 hyper-methylation during this time. This transcriptional memory is cis-encoded, as we identify a promoter fragment that confers memory onto a heterologous gene. In summary, heat-induced transcriptional memory is a widespread and sustained response, and our study provides a framework for future mechanistic studies of somatic stress memory in higher plants.
2018/11/19 10:30 AM
Dr. Chiao-Chun Liao (Dr.Shu-Mei Liang’s Lab)
The role of autophagy on the regulation of cells migration and ovarian cancer progression (ABRC Young Scientist Forum)
Auditorium A134, Agricultural Technology Building, Agricultural Biotechnology Research Center 2018/12/03 10:30 AM
Dr. Choun-Sea Lin (Research Specialist, Agricultural Biotechnology Research Center, Academia Sinica, Taiwan)
Auditorium A134, Agricultural Technology Building, Agricultural Biotechnology Research Center